DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG13532 and Skint1

DIOPT Version :9

Sequence 1:	NP_611728.1	Gene:	CG13532 / 37632	FlyBaseID:	FBgn0034788	Length:	263	Species:	Drosophila melanogaster
Sequence 2:	NP_001096132.1	Gene:	Skint1 / 639781	MGIID:	3649627	Length:	364	Species:	Mus musculus

Alignment Length:	257	Identity:	38/257 - (14%)
Similarity:	80/257 - (31%)	Gaps:	84/257 - (32%)

- Green bases have known domain annotations that are detailed below.

  Fly    48 LVLDCEVEIGPREQGFVLKWLFNNHS----------------IYQWIPSVKGFAMGFMKSKIDTK 96
            |.|.|::....:.|...::|..|.::                |.:::...:....|..:.|:..:
Mouse    45 LELSCQLSPPQQAQHMEIRWFRNLYTEPVHLYRDGKDMFGEIISKYVERTELLKDGIGEGKVTLR 109

  Fly    97 IFTMEGSPGVISIKNPDWNMT----GEYTCAVQTFESTDKRSARLQIIVPESDF----MLEARMS 153
            ||                |:|    |.|.|                 :..:.||    :.|.:::
Mouse   110 IF----------------NVTVDDDGSYHC-----------------VFKDGDFYEEHITEVKIT 141

  Fly   154 GSRMDVDIMCAVQHVFPQPMLSVMFDTH------------------ILDSVLTQLDQDPSGLYSM 200
            ...:.|.|     ||.|.....|:.:.|                  ::.:......|....|::|
Mouse   142 AINLQVQI-----HVHPPNTKGVIVECHSGGWFPRPLMQWRDRRGEVIPAASKSHSQGRDKLFNM 201

  Fly   201 TVRTRIPRDQLESPTPITCAFILVGTNYTKRRETIFYDKASTIQRKWTTV-AVVMSIASLAL 261
            .:...|.....:.   :.|......|...:|...|..|...:..|.|..: .:::|:..:::
Mouse   202 KISLLISESFFQK---VICCLQNPLTGQEERTSVILSDAFFSWNRIWKMILGIILSMMVVSI 260

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG13532	NP_611728.1	None
Skint1	NP_001096132.1	IGv domain	27..141		19/128 (15%)
		IG_like	35..140	CDD:214653	19/127 (15%)
		Ig_MOG_like	42..141	CDD:143190	19/128 (15%)
		IGc domain	142..228		13/93 (14%)
		transmembrane domain 1	247..269		1/14 (7%)
		transmembrane domain 2	282..304
		transmembrane domain 3	326..348
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.000