Protein Alignment fd59A and FHL1

DIOPT Version :10

• Sequence 1: NP_523814.1
• Gene: fd59A / 37631
• FlyBaseID: FBgn0004896
• Length: 456
• Species: Drosophila melanogaster
• Sequence 2: NP_015429.1
• Gene: FHL1 / 856219
• SGDID: S000006308
• Length: 936
• Species: Saccharomyces cerevisiae
• Alignment Length: 507
• Identity: 114/507 - (22%)
• Similarity: 151/507 - (29%)
• Gaps: 215/507 - (42%)

  Fly    85 KPPYSYIALITMAILQ-SPHKKLTLSGICDFIMSRFPYYKDKFPAWQNSIRHNLSLNDCFIKVPR 148
            ||..||.|::|..|.: |..|.::||.|...|...|||||.....||:|:|||||||..|.||.:
Yeast   461 KPTVSYSAMLTTCIRKYSTAKGMSLSEIYAGIRELFPYYKYCPDGWQSSVRHNLSLNKSFRKVSK 525

  Fly   149 EPGNPGKGNFWTLDP--LAE---------------------------------------DMFDNG 172
            |    |||..|.||.  :||                                       |:....
Yeast   526 E----GKGWLWGLDEEYIAERERQKKKQSEIAVAKAQAAQLKLEQQQHKLQQVPQRGKKDIVSQR 586

  Fly   173 SFLRRRKR-------YKRAP------------TMQRFSFPAVFGTLSPFWIRKPV---------- 208
            |.:..||:       ..||.            ||:......|..|.....:.|.|
Yeast   587 SNVNARKQNISQTLAANRAASNRKNTASDNQRTMKYLQEQLVILTRDRKGLSKQVIAAILTQALA 651

  Fly   209 ------------------PLV------PVHFNV---PNFNGSR------EFDVVHNPADVFDSAL 240
                              ||.      |.|.|:   ...|.:.      |...:.||.....:||
Yeast   652 MTINQVTQAAKNKGITGNPLTALMDKNPQHLNLILAAAVNAATAKVTKGEVKQLVNPETTAAAAL 716

  Fly   241 RA---------------------------------------DKKFNFFANAEAS-FYQGSQ---- 261
            .|                                       ||:...|..:..| |:|..|
Yeast   717 AAKAQHSKPIRQPIVQTPHVPDRPPSQLSASASSHPNNYLHDKQPGSFDPSSLSRFFQPRQNARA 781

  Fly   262 ------------SGDKFDRLPFMNRGRGADVLDALPHSSGSGGGVGGGSESSRGSKYKSPYAFDV 314
                        :....|..|.....:..|:......||.|......||||..||...|
Yeast   782 TSSVAATSVPAAASQNVDAQPKPKPAQDNDLESESGTSSSSSSSSESGSESDSGSDDGS------ 840

  Fly   315 ATVASAAGIPGHRDYAERLSAGGGYMDLNVYNDDADTEADAEAEGDDDSCED-------KIDVES 372
               ||.:|                        |::.|.:::|:|.|..|..|       |||.||
Yeast   841 ---ASGSG------------------------DNSSTSSESESESDSGSEVDEKNNKNEKIDSES 878

  Fly   373 --GNEQEDSHISDSVDSACTNRLDAPPEALIFEASAEASDSSPRRRFDSEPL 422
              .||.:|...|...:|:..||       .|.:...|..||  :||..||.:
Yeast   879 IKNNESKDDIPSKDENSSNDNR-------EISKTDEEGHDS--KRRKVSEDI 921

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
fd59A	NP_523814.1	FH_FOXD4-like	85..180	CDD:410822	43/136 (32%)
FHL1	NP_015429.1	COG5025	18..739	CDD:227358	64/281 (23%)