DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment fd59A and foxk2b

DIOPT Version :9

Sequence 1:	NP_523814.1	Gene:	fd59A / 37631	FlyBaseID:	FBgn0004896	Length:	456	Species:	Drosophila melanogaster
Sequence 2:	XP_001922856.1	Gene:	foxk2b / 798356	ZFINID:	ZDB-GENE-030131-5310	Length:	597	Species:	Danio rerio

Alignment Length:	216	Identity:	77/216 - (35%)
Similarity:	101/216 - (46%)	Gaps:	24/216 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly    13 DSVS--LSPPLIKSSRGGSSIGNGIGCSASSRTAAADAMSMGCDDSDIE---PSSMGGSGAAGGN 72
            |:::  :||  :.|..|..|..|  .|.:|.|.|.:....:|....|::   .:|...:......
Zfish   142 DNIAHLMSP--LPSPTGTISAAN--SCPSSPRGAGSSGYRLGRIVPDLQLMNDNSQSENDKETSE 202

  Fly    73 GDGSGSSGGPLVKPPYSYIALITMAILQSPHKKLTLSGICDFIMSRFPYYKDKFPAWQNSIRHNL 137
            ||......    ||||||..||..||..:|.|:|||:||...|...:|||:.....|||||||||
Zfish   203 GDSPKDDS----KPPYSYAQLIVQAITMAPDKQLTLNGIYTHITKNYPYYRTADKGWQNSIRHNL 263

  Fly   138 SLNDCFIKVPREPGNPGKGNFWTLDPLAEDMFDNGSFLRRRKRYKRAPTMQRFSFPAVFGTLSPF 202
            |||..||||||....||||:||.:||.:|......:|.:||.|          ..|.....|.|.
Zfish   264 SLNRYFIKVPRSQEEPGKGSFWRIDPSSEGKLVEQAFRKRRPR----------GVPCFRTPLGPL 318

  Fly   203 WIRKPVPLVPVHFNVPNFNGS 223
            ..|. .|..|.|..|.:.:.|
Zfish   319 SSRS-APASPNHSGVLSAHSS 338

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
fd59A	NP_523814.1	Forkhead	85..171	CDD:278670	48/85 (56%)
foxk2b	XP_001922856.1	FHA	17..109	CDD:238017
foxk2b	XP_001922856.1	Forkhead	211..297	CDD:278670	48/85 (56%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG2294
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1270467at2759
OrthoFinder	1	1.000	-	-		FOG0000010
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2114
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	5	4.850