DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment fd59A and Foxk2

DIOPT Version :9

Sequence 1:	NP_523814.1	Gene:	fd59A / 37631	FlyBaseID:	FBgn0004896	Length:	456	Species:	Drosophila melanogaster
Sequence 2:	XP_011247520.1	Gene:	Foxk2 / 68837	MGIID:	1916087	Length:	690	Species:	Mus musculus

Alignment Length:	217	Identity:	79/217 - (36%)
Similarity:	103/217 - (47%)	Gaps:	27/217 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 PMHTLHDSVSLSPPLIKSSRGGSSIGNGIGCSASSRTAAADAMSMGCDDSDIEPSSMGGSGAAGG 71
            |:.:...::|.:.....|.||..|.|..:|     |...:| :|:..|:|..|    ....|:||
Mouse   226 PLPSPTGTISAANSCPSSPRGAGSSGYKVG-----RVMPSD-LSLMADNSQPE----NEKEASGG 280

  Fly    72 NGDGSGSSGGPLVKPPYSYIALITMAILQSPHKKLTLSGICDFIMSRFPYYKDKFPAWQNSIRHN 136
            :.....|      ||||||..||..||..:|.|:|||:||...|...:|||:.....||||||||
Mouse   281 DSPKDDS------KPPYSYAQLIVQAITMAPDKQLTLNGIYTHITKNYPYYRTADKGWQNSIRHN 339

  Fly   137 LSLNDCFIKVPREPGNPGKGNFWTLDPLAEDMFDNGSFLRRRKRYKRAPTMQRFSFPAVFGTLSP 201
            ||||..||||||....||||:||.:||.:|......:|.:||.|          ..|.....|.|
Mouse   340 LSLNRYFIKVPRSQEEPGKGSFWRIDPASESKLVEQAFRKRRPR----------GVPCFRTPLGP 394

  Fly   202 FWIRKPVPLVPVHFNVPNFNGS 223
            ...|. .|..|.|..|.:.:.|
Mouse   395 LSSRS-APASPNHAGVLSAHSS 415

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
fd59A	NP_523814.1	Forkhead	85..171	CDD:278670	48/85 (56%)
Foxk2	XP_011247520.1	FHA	41..>124	CDD:238017
		COG5025	<175..>381	CDD:227358	67/170 (39%)
		Forkhead	287..373	CDD:365978	49/91 (54%)
		PHA03247	<380..683	CDD:223021	12/47 (26%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG2294
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1270467at2759
OrthoFinder	1	1.000	-	-		FOG0000010
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2114
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.850