DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment fd59A and foxf1

DIOPT Version :9

Sequence 1:	NP_523814.1	Gene:	fd59A / 37631	FlyBaseID:	FBgn0004896	Length:	456	Species:	Drosophila melanogaster
Sequence 2:	NP_001073655.1	Gene:	foxf1 / 566407	ZFINID:	ZDB-GENE-050419-153	Length:	380	Species:	Danio rerio

Alignment Length:	290	Identity:	97/290 - (33%)
Similarity:	132/290 - (45%)	Gaps:	98/290 - (33%)

- Green bases have known domain annotations that are detailed below.

  Fly    85 KPPYSYIALITMAILQSPHKKLTLSGICDFIMSRFPYYKDKFPAWQNSIRHNLSLNDCFIKVPRE 149
            ||||||||||.|||..||.|:||||.|..|:.||||:::..:..|:||:|||||||:||||:|:.
Zfish    52 KPPYSYIALIVMAIQSSPTKRLTLSEIYQFLQSRFPFFRGSYQGWKNSVRHNLSLNECFIKLPKG 116

  Fly   150 PGNPGKGNFWTLDPLAEDMFDNGSFLRRRKRYKRAPTMQRFSFPAVFGTLSPFWIRKPVPLVPVH 214
            .|.||||::||:||.:|.||:.|||.||.:.::                      ||...|.|..
Zfish   117 LGRPGKGHYWTIDPASEFMFEEGSFRRRPRGFR----------------------RKCQALKPSM 159

  Fly   215 FNVPN---FNGSREFDVVHNPADVFDSALRADKKFNFFANAEASFYQGS-------------QSG 263
            :::.|   ||        |.|           :.:||         ||.             :||
Zfish   160 YSMMNGLGFN--------HIP-----------ESYNF---------QGGGGGLSCPPNSLSLESG 196

  Fly   264 DKFDRLPFMNRGRGADVLD-------ALPH-SSGSGGGVGGGSESSRGSKYKSPYAFDVATVASA 320
                 :..|| |..|..::       ::|| |:.||....|....|.|::|
Zfish   197 -----IGMMN-GHLASNMEGMGLAGHSMPHLSTNSGHSYMGSCTGSSGTEY-------------- 241

  Fly   321 AGIPGHRDYAERLSAGGGYMDLN-VYNDDA 349
               |.|...|..|...||.||.: ||:..|
Zfish   242 ---PHHDSSASPLLTSGGVMDPHAVYSSTA 268

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
fd59A	NP_523814.1	Forkhead	85..171	CDD:278670	53/85 (62%)
foxf1	NP_001073655.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..49
foxf1	NP_001073655.1	FH	52..140	CDD:214627	53/87 (61%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG2294
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000010
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	4	3.810