DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment fd59A and foxo6a

DIOPT Version :9

Sequence 1:	NP_523814.1	Gene:	fd59A / 37631	FlyBaseID:	FBgn0004896	Length:	456	Species:	Drosophila melanogaster
Sequence 2:	XP_690041.2	Gene:	foxo6a / 561541	ZFINID:	ZDB-GENE-110914-126	Length:	594	Species:	Danio rerio

Alignment Length:	187	Identity:	63/187 - (33%)
Similarity:	85/187 - (45%)	Gaps:	50/187 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly    35 IGCSASSRTAAADAMSMGCD---------------DSDIEPSSMGGSGA----AGGNGDGSGSSG 80
            :|.:|.|.:...|   ..||               |||..||.......    |||..|.:|::
Zfish    19 LGSAARSCSWTND---FSCDVVNADLSLNLSIFQVDSDRAPSPSCRRRMMVLDAGGFHDLTGAA- 79

  Fly    81 GPLVKPP----------YSYIALITMAILQSPHKKLTLSGICDFIMSRFPYYKDK-----FPAWQ 130
              |.|..          .||..|||.||..:|.|:||||.|.|:::...||:|||     ...|:
Zfish    80 --LRKTKASSRRNAWGNQSYAELITRAIESTPDKRLTLSQIYDWMVRYVPYFKDKGDSNSSAGWK 142

  Fly   131 NSIRHNLSLNDCFIKVPREPGNPGKGNFWTLDPLAEDMFDNGSFLRRRKRYKRAPTM 187
            |||||||||:..||:|..|  ..||.::|.|:|       .|..|.:.:| :||.:|
Zfish   143 NSIRHNLSLHTRFIRVQNE--GTGKSSWWMLNP-------EGGKLGKSQR-RRAVSM 189

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
fd59A	NP_523814.1	Forkhead	85..171	CDD:278670	40/100 (40%)
foxo6a	XP_690041.2	FH	92..172	CDD:238016	37/81 (46%)
		PAT1	<390..>530	CDD:330585
		FOXO-TAD	528..568	CDD:318811
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.910