DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment fd59A and foxd3

DIOPT Version :9

Sequence 1:	NP_523814.1	Gene:	fd59A / 37631	FlyBaseID:	FBgn0004896	Length:	456	Species:	Drosophila melanogaster
Sequence 2:	NP_001011383.1	Gene:	foxd3 / 496851	XenbaseID:	XB-GENE-487289	Length:	369	Species:	Xenopus tropicalis

Alignment Length:	215	Identity:	115/215 - (53%)
Similarity:	134/215 - (62%)	Gaps:	34/215 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly    20 PLIKSSRGGSSIGNGIGCSASSRTAAADAMSMGCDDSDIEPSSMGGSGAAGGNGDGSGSSG---- 80
            ||.|.|..||..|:           |.:|..:|  ..:|..|..|.:..|.|.|:.....|
Frog    34 PLDKDSECGSPAGH-----------AEEADELG--GKEIARSPSGSANEAEGKGESQQQEGMQNK 85

  Fly    81 --GPLVKPPYSYIALITMAILQSPHKKLTLSGICDFIMSRFPYYKDKFPAWQNSIRHNLSLNDCF 143
              ..||||||||||||||||||||.|||||||||:||.:|||||::|||||||||||||||||||
Frog    86 PKNSLVKPPYSYIALITMAILQSPQKKLTLSGICEFISNRFPYYREKFPAWQNSIRHNLSLNDCF 150

  Fly   144 IKVPREPGNPGKGNFWTLDPLAEDMFDNGSFLRRRKRYKR----------APTMQRFSFPAVFGT 198
            :|:|||||||||||:|||||.:|||||||||||||||:||          |..||.|   ..:..
Frog   151 VKIPREPGNPGKGNYWTLDPQSEDMFDNGSFLRRRKRFKRQQPDSLREQTALMMQSF---GAYSL 212

  Fly   199 LSPFWIRKPVPLVPVHFNVP 218
            ..|:  .:|..|.|..:..|
Frog   213 AGPY--GRPYGLHPAAYTHP 230

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
fd59A	NP_523814.1	Forkhead	85..171	CDD:278670	74/85 (87%)
foxd3	NP_001011383.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..89		17/67 (25%)
foxd3	NP_001011383.1	Forkhead	92..177	CDD:365978	73/84 (87%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1270467at2759
OrthoFinder	1	1.000	-	-		FOG0000010
OrthoInspector	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	LDO	PTHR11829
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2114
SonicParanoid	1	1.000	-	-		X1212
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	6	6.050