DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment fd59A and fd102C

DIOPT Version :9

Sequence 1:	NP_523814.1	Gene:	fd59A / 37631	FlyBaseID:	FBgn0004896	Length:	456	Species:	Drosophila melanogaster
Sequence 2:	NP_651951.1	Gene:	fd102C / 43843	FlyBaseID:	FBgn0039937	Length:	599	Species:	Drosophila melanogaster

Alignment Length:	511	Identity:	121/511 - (23%)
Similarity:	180/511 - (35%)	Gaps:	136/511 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly    40 SSRTAAADAMSMGCDDSDIE-------------P--SSMGGSGAA---------GGNGDGSGSSG 80
            ::||:.|.:.:|..:...::             |  ...|||||:         |.:|.||..|.
  Fly    40 TTRTSQAQSTTMTLEQYRLQLYNYALNIERLRCPQYGGTGGSGASAPWLHLSPYGHHGSGSLPSV 104

  Fly    81 GPLV--------------------KPPYSYIALITMAILQSPHKKLTLSGICDFIMSRFPYYKDK 125
            ..:.                    ||.:|||.||.||||.|...||.||.|..:|:..:||::.:
  Fly   105 NRMAALSTISLFPQTQRIFQPEEPKPQHSYIGLIAMAILSSTDMKLVLSDIYQYILDNYPYFRSR 169

  Fly   126 FPAWQNSIRHNLSLNDCFIKVPREPGNPGKGNFWTLDPLAEDMFDNGSFLRRRKRYKRAPTMQRF 190
            .|.|:|||||||||||||||..|...  |||::|.:.|...:.|..|.| ||||..::.......
  Fly   170 GPGWRNSIRHNLSLNDCFIKSGRSAN--GKGHYWAIHPANMEDFRKGDF-RRRKAQRKVRKHMGL 231

  Fly   191 SFPAVFGTLSPFWIRKPVPL--------------------VPVH-------FNVPNFNGSREFD- 227
            |.... .|.||    .|.||                    .|.|       ||..:..|...:.
  Fly   232 SVDDA-STDSP----SPPPLDLTTPPPPSSQSALQLSALGYPYHQHYIGQFFNRSSAPGMTHYSP 291

  Fly   228 ------VVHNPADVFDSALRADKKFNFFANAEASFYQGSQSGDKFDRLPFMNRGRGADVLDALPH 286
                  :....|:..|..::..:.....::.:...|..|.:......:....|.|..||...|..
  Fly   292 PDPALLMQRQEANNLDQTIQPTQLQQPHSHHQHFAYINSTTTTTIANMFSQTRKRQFDVASLLAP 356

  Fly   287 SSGSGGGVGGGSESS----RGSKYKSPYAFDVATVASAAGIPGHRDYAERLSAGGGYMDLNVYND 347
            .......|....|||    ..::..:.....|.|..:.     ||:..         :.|.....
  Fly   357 DVQIVDIVSEDQESSVTPTTSARTTTQTHHTVITKQTI-----HREVV---------LGLEKPVQ 407

  Fly   348 DADTEADAEAEGDDDSCEDKI--DVESGNEQEDS-----------HISDSVDSACTNRLDAPPEA 399
            |||.:||.:.|.:.|..:|.|  |.:|..:.||.           .|.|:             .:
  Fly   408 DADIDADIDVEVNVDVVDDSIIPDTDSYTDGEDRKKTRGTLKQIFSIEDN-------------NS 459

  Fly   400 LIFEASAEASDSSPRRRFDSEPLVLRTSKQSSAKDFRIETLIGHHLHRGGSQEETS 455
            .:.:....:.|:.|....|.:|      :.....:|.|.:.....|....||.|.|
  Fly   460 YLIDGRLSSFDADPDHDPDHDP------EDLEQHNFSIASSAARSLGSSSSQHEES 509

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
fd59A	NP_523814.1	Forkhead	85..171	CDD:278670	44/85 (52%)
fd102C	NP_651951.1	Forkhead	129..213	CDD:278670	44/85 (52%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45445483
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG2294
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1270467at2759
OrthoFinder	1	1.000	-	-		FOG0000010
OrthoInspector	1	1.000	-	-		otm46670
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11829
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2114
SonicParanoid	0	0.000	Not matched by this tool.
	8	7.880