DRSC/TRiP Functional Genomics Resources

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Protein Alignment fd59A and FOXI2

DIOPT Version :9

Sequence 1:NP_523814.1 Gene:fd59A / 37631 FlyBaseID:FBgn0004896 Length:456 Species:Drosophila melanogaster
Sequence 2:NP_997309.2 Gene:FOXI2 / 399823 HGNCID:32448 Length:318 Species:Homo sapiens


Alignment Length:323 Identity:108/323 - (33%)
Similarity:139/323 - (43%) Gaps:99/323 - (30%)


- Green bases have known domain annotations that are detailed below.


  Fly    49 MSMGCDDSDIEPSSM----------------GGSGAAGG-----------------NGDGS---- 76
            |:..||  |:.|||.                |..||.||                 :|.|.    
Human     1 MATYCD--DLGPSSAPPGQAQATAHPPGYEPGDLGAVGGGPLLWVNAPALSPKSYASGPGPAPPY 63

  Fly    77 ------------GSSGG------------------PLVKPPYSYIALITMAILQSPHKKLTLSGI 111
                        |:.||                  .||:|||||.|||.|||..:|.:|||||.|
Human    64 AAPSYGAPGPLLGAPGGLAGADLAWLSLSGQQELLRLVRPPYSYSALIAMAIQSAPLRKLTLSQI 128

  Fly   112 CDFIMSRFPYYKDKFPAWQNSIRHNLSLNDCFIKVPREPGNPGKGNFWTLDPLAEDMFDNGSFLR 176
            ..::...||:||.....|||||||||||||||.||||:..:|||||:|||||..|.|||||:|.|
Human   129 YQYVAGNFPFYKRSKAGWQNSIRHNLSLNDCFKKVPRDEDDPGKGNYWTLDPNCEKMFDNGNFRR 193

  Fly   177 RRKRYKRAPTMQRFSFPAVFGTLSPFWIRKPVPLVPVHFNVPNFNGSREFDVVHNPADVFDSALR 241
            :|||...|....|....:|.|..:|       .|.|     |:   :...|:..:|:   .||..
Human   194 KRKRRAEASAAVRSGARSVGGAEAP-------ALEP-----PS---AACLDLQASPS---PSAPE 240

  Fly   242 ADKKFNFFANAEASF------YQGSQSGD-KFDRLPFMNRGRGADVLDALP-----HSSGSGG 292
            |...|:.||:|.::.      :.|..:|| .|.|.|..........|:..|     |.:.:.|
Human   241 AATCFSGFASAMSALAGGLGTFPGGLAGDFSFGRRPPTVATHAPQTLNPSPGFAPGHQTAAAG 303

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
fd59ANP_523814.1 Forkhead 85..171 CDD:278670 54/85 (64%)
FOXI2NP_997309.2 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1..30 7/30 (23%)
Forkhead 102..188 CDD:278670 54/85 (64%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E2759_KOG2294
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 1 1.010 - - D1270467at2759
OrthoFinder 1 1.000 - - FOG0000010
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
43.820

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