Protein Alignment fd59A and FOXN2

DIOPT Version :10

• Sequence 1: NP_523814.1
• Gene: fd59A / 37631
• FlyBaseID: FBgn0004896
• Length: 456
• Species: Drosophila melanogaster
• Sequence 2: NP_002149.2
• Gene: FOXN2 / 3344
• HGNCID: 5281
• Length: 431
• Species: Homo sapiens
• Alignment Length: 339
• Identity: 86/339 - (25%)
• Similarity: 123/339 - (36%)
• Gaps: 117/339 - (34%)

  Fly    77 GSSGGPLV-----------------------------KPPYSYIALITMAILQSPHKKLTLSGIC 112
            ||.|.|:|                             |||||:..||.|||..||:|.|.:..|.
Human    75 GSEGLPIVSPLYDIEGDDVPSFGPACYQNPEKKSATSKPPYSFSLLIYMAIEHSPNKCLPVKEIY 139

  Fly   113 DFIMSRFPYYKDKFPAWQNSIRHNLSLNDCFIKVPREPGN-PGKGNFWTLDPLAEDMFDNGSFLR 176
            .:|:..|||:......|:||:|||||||.||.||.|..|. .|||:.|.:||
Human   140 SWILDHFPYFATAPTGWKNSVRHNLSLNKCFQKVERSHGKVNGKGSLWCVDP------------- 191

  Fly   177 RRKRYK----RAPTMQRF-SFPAVFGTLSPFWI-------------------------------- 204
               .||    :|...|.| |..:..|:|||.::
Human   192 ---EYKPNLIQALKKQPFSSASSQNGSLSPHYLSSVIKQNQVRNLKESDIDAAAAMMLLNTSIEQ 253

  Fly   205 -----RKPVPLVPVHFNVPNFNGSREF-DVVHNP-------ADVFDSALRADKKFNFFANAEASF 256
                 .||:||...      ....|.: :..|:|       :|...:::...:..|:.|::.|:
Human   254 GILECEKPLPLKTA------LQKKRSYGNAFHHPSAVRLQESDSLATSIDPKEDHNYSASSMAA- 311

  Fly   257 YQGSQSGDKFDRLPFMNRGRGADVLDALPHSS--GSGGGVGGGSESSRGSKYK------SPYAFD 313
             |...|......|..::     :|.:.:|.:|  ||.|..|..||......|:      |.||..
Human   312 -QRCASRSSVSSLSSVD-----EVYEFIPKNSHVGSDGSEGFHSEEDTDVDYEDDPLGDSGYASQ 370

  Fly   314 VATVASAAGIPGHR 327
            .....|..|..|.:
Human   371 PCAKISEKGQSGKK 384

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
fd59A	NP_523814.1	FH_FOXD4-like	85..180	CDD:410822	41/95 (43%)
FOXN2	NP_002149.2	FH_FOXN2	111..192	CDD:410832	41/96 (43%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	364..387		6/21 (29%)