DRSC/TRiP Functional Genomics Resources

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Protein Alignment fd59A and Foxo6

DIOPT Version :10

Sequence 1:NP_523814.1 Gene:fd59A / 37631 FlyBaseID:FBgn0004896 Length:456 Species:Drosophila melanogaster
Sequence 2:NP_918949.1 Gene:Foxo6 / 329934 MGIID:2676586 Length:559 Species:Mus musculus


Alignment Length:341 Identity:93/341 - (27%)
Similarity:130/341 - (38%) Gaps:97/341 - (28%)


- Green bases have known domain annotations that are detailed below.


  Fly    65 GSGAAGGNGDGS----------------GSSGGPLVKPP---------YSYIALITMAILQSPHK 104
            |:|.|.|:.|..                |:..|||.|..         .||..|||.||..:|.|
Mouse    43 GAGVAEGSEDCGPERRATAPAMAPAPPLGAEVGPLRKAKSSRRNAWGNLSYADLITKAIESAPDK 107

  Fly   105 KLTLSGICDFIMSRFPYYKDK-----FPAWQNSIRHNLSLNDCFIKVPREPGNPGKGNFWTLDP- 163
            :||||.|.|:::...||:|||     ...|:|||||||||:..||:|..|  ..||.::|.|:| 
Mouse   108 RLTLSQIYDWMVRYVPYFKDKGDSNSSAGWKNSIRHNLSLHTRFIRVQNE--GTGKSSWWMLNPE 170

  Fly   164 ----------LAEDMFDNGS-FLR-----RRKRYKRAPTMQRFSFP---AVFGTLSPF--WIRKP 207
                      .|..| |||: |||     .:|:....|.......|   .|.|.||..  |...|
Mouse   171 GGKTGKTPRRRAVSM-DNGAKFLRIKGKASKKKQLHLPERSPDDSPPGAPVPGPLSASAKWAASP 234

  Fly   208 VPLVPVHFNV-PNFNGSREFDVVHNPADVFDSALRADKKFNFFANAEASFYQGSQSGDKFDRLPF 271
            .......:.. .:|.|||. .::...|::.|     |:.....|.:....|....|.        
Mouse   235 ASHASDDYEAWADFRGSRR-PLLGEAAELED-----DEALEALAPSSPLMYPSPASA-------- 285

  Fly   272 MNRGRGADVLDALPHSSG-------SGGGVGG-------GSESSRGSKYKSPYAFDVATVASAAG 322
            ::...||.....||..:.       .||||.|       |::.:.|.:             :.||
Mouse   286 LSPALGARCPGELPRLAELGGPLGLHGGGVAGLPDALLDGAQDAYGPR-------------ARAG 337

  Fly   323 IPGHRDYAERLSAGGG 338
            .|.:....:..:.|||
Mouse   338 TPSYFGSCKASAYGGG 353

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
fd59ANP_523814.1 FH_FOXD4-like 85..180 CDD:410822 48/125 (38%)
Foxo6NP_918949.1 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1..77 7/33 (21%)
FH_FOXO6 89..176 CDD:410837 39/88 (44%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 163..183 3/19 (16%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 197..232 8/34 (24%)
FOXO_KIX_bdg 358..>380 CDD:465228
FOXO-TAD 499..537 CDD:435506
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 534..559
Blue background indicates that the domain is not in the aligned region.

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