DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment fd59A and foxa3

DIOPT Version :9

Sequence 1:	NP_523814.1	Gene:	fd59A / 37631	FlyBaseID:	FBgn0004896	Length:	456	Species:	Drosophila melanogaster
Sequence 2:	NP_571374.1	Gene:	foxa3 / 30559	ZFINID:	ZDB-GENE-980526-423	Length:	441	Species:	Danio rerio

Alignment Length:	210	Identity:	84/210 - (40%)
Similarity:	108/210 - (51%)	Gaps:	49/210 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 STDPMHTLHDSVSL-SPPLIKSSRGGSSIGNGIGCSASSRTAAADAMSMGCDDSDIEPSS---MG 64
            ||..|:..:.|..| |.||       ||:|.|           .:.||:....|.:.|||   :|
Zfish    49 STSSMNMGYPSAGLNSSPL-------SSMGGG-----------PNHMSLSPVGSSLNPSSLTQLG 95

  Fly    65 GSGAAGGNGDGSGSSGGPL---------------------------VKPPYSYIALITMAILQSP 102
            .|.:..|......|.|.|:                           .|||||||:||||||.||.
Zfish    96 SSASTLGPLSHYQSMGQPMSQISYPSPTSLNRTKEMPKPYRRSLTHAKPPYSYISLITMAIQQSQ 160

  Fly   103 HKKLTLSGICDFIMSRFPYYKDKFPAWQNSIRHNLSLNDCFIKVPREPGNPGKGNFWTLDPLAED 167
            .|.|||:.|..:||..||||::....|||||||:||.||||:||.|.|..||||::|.|.|.:.:
Zfish   161 SKMLTLNEIYQWIMDLFPYYRENQQRWQNSIRHSLSFNDCFVKVARSPDKPGKGSYWALHPNSGN 225

  Fly   168 MFDNGSFLRRRKRYK 182
            ||:||.:|||:||:|
Zfish   226 MFENGCYLRRQKRFK 240

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
fd59A	NP_523814.1	Forkhead	85..171	CDD:278670	52/85 (61%)
foxa3	NP_571374.1	Forkhead_N	17..142	CDD:254796	24/110 (22%)
		FH	143..231	CDD:214627	53/87 (61%)
		HNF_C	374..>408	CDD:286443
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000010
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.910