DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment fd59A and Foxh1

DIOPT Version :9

Sequence 1:	NP_523814.1	Gene:	fd59A / 37631	FlyBaseID:	FBgn0004896	Length:	456	Species:	Drosophila melanogaster
Sequence 2:	XP_008763787.1	Gene:	Foxh1 / 300054	RGDID:	1311275	Length:	416	Species:	Rattus norvegicus

Alignment Length:	265	Identity:	68/265 - (25%)
Similarity:	108/265 - (40%)	Gaps:	66/265 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly    85 KPPYSYIALITMAILQSPHKKLTLSGICDFIMSRFPYYKDKFPAWQNSIRHNLSLNDCFIKVPRE 149
            ||||:|:|:|.:.|.|              :.:.||:::|.:..|::|||||||.|.||.|||::
  Rat    93 KPPYTYLAMIALIIRQ--------------VQAVFPFFRDDYEGWKDSIRHNLSSNRCFRKVPKD 143

  Fly   150 PGNP-GKGNFWTLD----PLAEDMFDNGSFLRRRKRYKRAPTMQRFSFPAVFGTLSPFWI----- 204
            |..| .|||||.:|    |.......|.:..|   |::...|.:.|:     ..|||:.:
  Rat   144 PAKPQAKGNFWAVDVSLIPAEALRLQNTALCR---RWQNRGTHRAFA-----KDLSPYVLHGQPY 200

  Fly   205 RKPVPLVPVH--FNVPNFNG---------------------------SREFDVVHNPADVFDSAL 240
            |.|.|..|..  |::.:..|                           ..|..:...|::|.|..|
  Rat   201 RPPSPPPPSREDFSIKSLLGDPGKASTWPQHPRLAGQSTPAQASTLSKGEEGIGAGPSNVSDKPL 265

  Fly   241 RADKKFNFFANAEASFYQGSQSGDKFDRLPFMNRGRGADVLDALPHSSGSGGGVGGGSESSRGSK 305
                 :...:....:..:|..|..:..|...::..:|:..|..|..||.|.|....||.:|...:
  Rat   266 -----WPLSSLPRPTRIEGETSQGEVIRPSPVSSDQGSWPLHLLQDSSDSMGMSRRGSRASLWGQ 325

  Fly   306 YKSPY 310
            ..:.|
  Rat   326 LPTSY 330

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
fd59A	NP_523814.1	Forkhead	85..171	CDD:278670	35/90 (39%)
Foxh1	XP_008763787.1	FH	93..157	CDD:294049	33/77 (43%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG2294
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1270467at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.820