DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment fd59A and Foxi2

DIOPT Version :9

Sequence 1:	NP_523814.1	Gene:	fd59A / 37631	FlyBaseID:	FBgn0004896	Length:	456	Species:	Drosophila melanogaster
Sequence 2:	NP_899016.2	Gene:	Foxi2 / 270004	MGIID:	3028075	Length:	311	Species:	Mus musculus

Alignment Length:	196	Identity:	88/196 - (44%)
Similarity:	107/196 - (54%)	Gaps:	23/196 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly    19 PPLIKSSRGGSSIGNG----IGCSASS----RTAAADAMSMGCDDSDIEPSSMGGSGAAGGNGDG 75
            ||    |.|.:.:.:|    :..:|.|    .|....|.|.......:..|.:|.||...|....
Mouse    24 PP----SYGRTDLSSGRRLWVNSAALSPAPYATGPGPAPSYAAATLAVPGSLLGASGGLAGADLA 84

  Fly    76 SGSSGGP-----LVKPPYSYIALITMAILQSPHKKLTLSGICDFIMSRFPYYKDKFPAWQNSIRH 135
            ..|..|.     ||:|||||.|||.|||..:|.::||||.|..::...||:||.....|||||||
Mouse    85 WLSLSGQQELLRLVRPPYSYSALIAMAIQSAPLRRLTLSQIYQYVAGNFPFYKRSKAGWQNSIRH 149

  Fly   136 NLSLNDCFIKVPREPGNPGKGNFWTLDPLAEDMFDNGSFLRRRKRYKRAPTMQRFSFPAVFGTLS 200
            ||||||||.||||:..:|||||:|||||..|.|||||:|  ||||.:|..|    |..||.|..|
Mouse   150 NLSLNDCFKKVPRDENDPGKGNYWTLDPNCEKMFDNGNF--RRKRRRRGET----SEAAVPGASS 208

  Fly   201 P 201
            |
Mouse   209 P 209

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
fd59A	NP_523814.1	Forkhead	85..171	CDD:278670	53/85 (62%)
Foxi2	NP_899016.2	Forkhead	99..184	CDD:333958	52/84 (62%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	188..237		13/28 (46%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	263..294
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG2294
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1270467at2759
OrthoFinder	1	1.000	-	-		FOG0000010
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	5	4.820