DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment fd59A and Foxl2

DIOPT Version :9

Sequence 1:	NP_523814.1	Gene:	fd59A / 37631	FlyBaseID:	FBgn0004896	Length:	456	Species:	Drosophila melanogaster
Sequence 2:	NP_036150.1	Gene:	Foxl2 / 26927	MGIID:	1349428	Length:	375	Species:	Mus musculus

Alignment Length:	174	Identity:	82/174 - (47%)
Similarity:	98/174 - (56%)	Gaps:	41/174 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly    59 EPSSMGG------SGAAGGNGDGS----GSSGG-------PLVKPPYSYIALITMAILQSPHKKL 106
            ||....|      ||.|....:.|    |..||       |..||||||:|||.|||.:|..|:|
Mouse     7 EPEDTAGTLLAPESGRAVKEAEASPPSPGKGGGTTPEKPDPAQKPPYSYVALIAMAIRESAEKRL 71

  Fly   107 TLSGICDFIMSRFPYYKDKFPAWQNSIRHNLSLNDCFIKVPREPGNPGKGNFWTLDPLAEDMFDN 171
            |||||..:|:::||:|:.....||||||||||||:||||||||.|...|||:|||||..||||:.
Mouse    72 TLSGIYQYIIAKFPFYEKNKKGWQNSIRHNLSLNECFIKVPREGGGERKGNYWTLDPACEDMFEK 136

  Fly   172 GSFLRRRKRYKRAPTMQRFSFPAVFGTLSPFWIRKPVPLVPVHF 215
            |:: |||:|.||                 ||  |.|    |.||
Mouse   137 GNY-RRRRRMKR-----------------PF--RPP----PAHF 156

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
fd59A	NP_523814.1	Forkhead	85..171	CDD:278670	57/85 (67%)
Foxl2	NP_036150.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..50		11/42 (26%)
		FH	50..138	CDD:214627	57/87 (66%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	272..341
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG2294
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1270467at2759
OrthoFinder	1	1.000	-	-		FOG0000010
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.820