DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment fd59A and FOXS1

DIOPT Version :9

Sequence 1:	NP_523814.1	Gene:	fd59A / 37631	FlyBaseID:	FBgn0004896	Length:	456	Species:	Drosophila melanogaster
Sequence 2:	NP_004109.1	Gene:	FOXS1 / 2307	HGNCID:	3735	Length:	330	Species:	Homo sapiens

Alignment Length:	152	Identity:	76/152 - (50%)
Similarity:	95/152 - (62%)	Gaps:	9/152 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly    75 GSGSSGGPLVKPPYSYIALITMAILQSPHKKLTLSGICDFIMSRFPYYKDKFPAWQNSIRHNLSL 139
            |.|:......||||||||||.|||..||.::.|||||..:||.||.:|:...|.|||||||||||
Human     8 GPGAPTTEPTKPPYSYIALIAMAIQSSPGQRATLSGIYRYIMGRFAFYRHNRPGWQNSIRHNLSL 72

  Fly   140 NDCFIKVPREPGNPGKGNFWTLDPLAEDMFDNGSFLRRRKRYKRAPTMQRFSFPAVFGTLSPFWI 204
            |:||:||||:...||||::|||||...|||::|||||||:|:.|....:        ||..|...
Human    73 NECFVKVPRDDRKPGKGSYWTLDPDCHDMFEHGSFLRRRRRFTRQTGAE--------GTRGPAKA 129

  Fly   205 RK-PVPLVPVHFNVPNFNGSRE 225
            |: |:........|||....|:
Human   130 RRGPLRATSQDPGVPNATTGRQ 151

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
fd59A	NP_523814.1	Forkhead	85..171	CDD:278670	56/85 (66%)
FOXS1	NP_004109.1	Forkhead	18..103	CDD:306709	55/84 (65%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	111..157		12/49 (24%)
		DNA_pol3_gamma3	<116..313	CDD:331207	10/44 (23%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	179..200
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG2294
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1270467at2759
OrthoFinder	1	1.000	-	-		FOG0000010
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	4	3.820