Protein Alignment fd59A and FOXL1

DIOPT Version :10

• Sequence 1: NP_523814.1
• Gene: fd59A / 37631
• FlyBaseID: FBgn0004896
• Length: 456
• Species: Drosophila melanogaster
• Sequence 2: NP_005241.1
• Gene: FOXL1 / 2300
• HGNCID: 3817
• Length: 345
• Species: Homo sapiens
• Alignment Length: 282
• Identity: 103/282 - (36%)
• Similarity: 134/282 - (47%)
• Gaps: 78/282 - (27%)

  Fly    76 SGSSGGPLVKPPYSYIALITMAILQSPHKKLTLSGICDFIMSRFPYYKDKFPAWQNSIRHNLSLN 140
            ||.:..| .||||||||||.|||..:|.:::||:||..|||.|||:|.|....||||||||||||
Human    41 SGRAETP-QKPPYSYIALIAMAIQDAPEQRVTLNGIYQFIMDRFPFYHDNRQGWQNSIRHNLSLN 104

  Fly   141 DCFIKVPREPGNPGKGNFWTLDPLAEDMFDNGSFLRRRKRYK-----------RAPTMQRF---- 190
            |||:|||||.|.||||::|||||...|||:||::.||:::.|           ||.|.||.
Human   105 DCFVKVPREKGRPGKGSYWTLDPRCLDMFENGNYRRRKRKPKPGPGAPEAKRPRAETHQRSAEAQ 169

  Fly   191 ---------SFPAVF------GTLSPFWIRKPVPLVPVHFNVPNFNGSREFDVVHNPADVFDSAL 240
                     |.||:.      ...||. :..|.|..|:|:  |......|        |..|:|.
Human   170 PEAGSGAGGSGPAISRLQAAPAGPSPL-LDGPSPPAPLHW--PGTASPNE--------DAGDAAQ 223

  Fly   241 RADKKFNFFANAEASFYQGSQSGDKFDRLPFMNRGRGADVLDALPHSSGSGGGVGGGSESSRGSK 305
            .|         |..:..|.:::||                        |.|..:...|.||..|.
Human   224 GA---------AAVAVGQAARTGD------------------------GPGSPLRPASRSSPKSS 255

  Fly   306 YKSPYAFDVATVASAAGIPGHR 327
            .||. :|.:.::  .||..|.:
Human   256 DKSK-SFSIDSI--LAGKQGQK 274

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
fd59A	NP_523814.1	FH_FOXD4-like	85..180	CDD:410822	63/94 (67%)
FOXL1	NP_005241.1	FH_FOXL1	47..144	CDD:410801	64/97 (66%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	136..289		40/186 (22%)