| Sequence 1: | NP_523814.1 | Gene: | fd59A / 37631 | FlyBaseID: | FBgn0004896 | Length: | 456 | Species: | Drosophila melanogaster |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_001444.2 | Gene: | FOXC1 / 2296 | HGNCID: | 3800 | Length: | 553 | Species: | Homo sapiens |
| Alignment Length: | 440 | Identity: | 127/440 - (28%) |
|---|---|---|---|
| Similarity: | 171/440 - (38%) | Gaps: | 182/440 - (41%) |
- Green bases have known domain annotations that are detailed below.
|
Fly 60 PSSMG-------------GSGAAGGNG---------------------DGSGSSGGP-------- 82
Fly 83 -LVKPPYSYIALITMAILQSPHKKLTLSGICDFIMSRFPYYKDKFPAWQNSIRHNLSLNDCFIKV 146
Fly 147 PREPGNPGKGNFWTLDPLAEDMFDNGSFLRRRKRYKR---------------------------A 184
Fly 185 PTMQR------------------------------FSFPAVFGTLSPFWIRK------------- 206
Fly 207 ----------------------PVPLVPVHFNVPNFNGSREFDVVHNPADVFDSALR-------A 242
Fly 243 DKKFNFFANAEASFYQGSQSGDKFDRLPFMNRGR---GADVLDALP----HSSGSGGGVGGGSES 300
Fly 301 SRGSKYKSPYAFDVATVASAA---------GIPGHRDYAERLSAGGGYMD 341 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| fd59A | NP_523814.1 | Forkhead | 85..171 | CDD:278670 | 58/85 (68%) |
| FOXC1 | NP_001444.2 | Required for transcriptional activation. /evidence=ECO:0000269|PubMed:11782474 | 1..51 | 7/40 (18%) | |
| FH | 78..166 | CDD:214627 | 59/87 (68%) | ||
| Nuclear localization signal 1 (NLS 1). /evidence=ECO:0000269|PubMed:11782474 | 78..93 | 14/14 (100%) | |||
| Nuclear localization signal 2 (NLS 2). /evidence=ECO:0000269|PubMed:11782474 | 168..176 | 5/7 (71%) | |||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 173..310 | 16/139 (12%) | |||
| Required for transcriptional inhibition. /evidence=ECO:0000269|PubMed:11782474 | 215..366 | 27/166 (16%) | |||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 356..387 | 11/30 (37%) | |||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 414..465 | 7/20 (35%) | |||
| Required for transcriptional activation. /evidence=ECO:0000269|PubMed:11782474 | 466..553 | ||||
| Blue background indicates that the domain is not in the aligned region. | |||||
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 0 | 0.000 | Not matched by this tool. | |||
| Domainoid | 0 | 0.000 | Not matched by this tool. | |||
| eggNOG | 0 | 0.000 | Not matched by this tool. | |||
| Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
| Homologene | 0 | 0.000 | Not matched by this tool. | |||
| Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
| Isobase | 0 | 0.000 | Not matched by this tool. | |||
| OMA | 0 | 0.000 | Not matched by this tool. | |||
| OrthoDB | 1 | 1.010 | - | - | D1270467at2759 | |
| OrthoFinder | 1 | 1.000 | - | - | FOG0000010 | |
| OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
| orthoMCL | 0 | 0.000 | Not matched by this tool. | |||
| Panther | 0 | 0.000 | Not matched by this tool. | |||
| Phylome | 1 | 0.910 | - | - | ||
| RoundUp | 0 | 0.000 | Not matched by this tool. | |||
| SonicParanoid | 0 | 0.000 | Not matched by this tool. | |||
| SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
| TreeFam | 0 | 0.000 | Not matched by this tool. | |||
| User_Submission | 0 | 0.000 | Not matched by this tool. | |||
| 3 | 2.920 | |||||