DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment fd59A and Foxe3

DIOPT Version :9

Sequence 1:	NP_523814.1	Gene:	fd59A / 37631	FlyBaseID:	FBgn0004896	Length:	456	Species:	Drosophila melanogaster
Sequence 2:	NP_599166.1	Gene:	Foxe3 / 171302	RGDID:	621727	Length:	286	Species:	Rattus norvegicus

Alignment Length:	195	Identity:	90/195 - (46%)
Similarity:	111/195 - (56%)	Gaps:	40/195 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    50 SMGCDDSDIEPSSMGGSGAAGGNGDGSGSSG------GPLV--KPPYSYIALITMAILQSPHKKL 106
            |:..|:...||..:.|    ||:.:...:.|      .||.  ||||||||||.||:..:|.::|
  Rat    25 SLAGDEPGREPEEVVG----GGDSEPPAAPGPGRRRRRPLQRGKPPYSYIALIAMALAHAPGRRL 85

  Fly   107 TLSGICDFIMSRFPYYKDKFPAWQNSIRHNLSLNDCFIKVPREPGNPGKGNFWTLDPLAEDMFDN 171
            ||:.|..||..||.:|:|....|||||||||:|||||:|||||||||||||:|||||.|.|||||
  Rat    86 TLAAIYRFITERFAFYRDSPRKWQNSIRHNLTLNDCFVKVPREPGNPGKGNYWTLDPAAADMFDN 150

  Fly   172 GSFLRRRKRYKR------------------------APTMQRFSFPAVFGTLSPFWIRKPVPLVP 212
            |||||||||:||                        ||..:.|...::.|..:    ..|.||.|
  Rat   151 GSFLRRRKRFKRTELPAPPPPPFPYAPFPPAPAPAPAPPARLFRLDSLLGLQT----EPPGPLAP 211

Fly 213 212
Rat 212 211

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
fd59A	NP_523814.1	Forkhead	85..171	CDD:278670	59/85 (69%)
Foxe3	NP_599166.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..62		10/40 (25%)
Foxe3	NP_599166.1	FH	64..152	CDD:214627	61/87 (70%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG2294
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1270467at2759
OrthoFinder	1	1.000	-	-		FOG0000010
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11829
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	6	5.920