DRSC/TRiP Functional Genomics Resources

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Protein Alignment fd59A and Foxb2

DIOPT Version :9

Sequence 1:NP_523814.1 Gene:fd59A / 37631 FlyBaseID:FBgn0004896 Length:456 Species:Drosophila melanogaster
Sequence 2:NP_032049.1 Gene:Foxb2 / 14240 MGIID:1347468 Length:428 Species:Mus musculus


Alignment Length:306 Identity:105/306 - (34%)
Similarity:129/306 - (42%) Gaps:86/306 - (28%)


- Green bases have known domain annotations that are detailed below.


  Fly    85 KPPYSYIALITMAILQSPHKKLTLSGICDFIMSRFPYYKDKFPAWQNSIRHNLSLNDCFIKVPRE 149
            |||||||:|..|||..|..|.|.||.|..|||.|||||::....||||:|||||.||||||:||.
Mouse    13 KPPYSYISLTAMAIQHSAEKMLPLSDIYKFIMERFPYYREHTQRWQNSLRHNLSFNDCFIKIPRR 77

  Fly   150 PGNPGKGNFWTLDPLAEDMFDNGSFLRRRKRYK--RAPTMQRFS-----FPAV--FGTLSPFWIR 205
            |..||||:||.|.|...|||:||||||||||:|  ||......|     .|..  .|.|.|....
Mouse    78 PDQPGKGSFWALHPDCGDMFENGSFLRRRKRFKVLRADHAHLHSGSSKGAPGTGPGGHLHPHHPH 142

  Fly   206 ----------------------KPVPLVPVHFNVPNFN----------------------GSREF 226
                                  :|.|..|.|. ||.|:                      .|:..
Mouse   143 HAHHHHHHHHHAAHHHHHHHPPQPPPPPPPHM-VPYFHQQPAPAPQPPHLPSQPAQQPQPQSQPP 206

  Fly   227 DVVHNPADVFDSALRADKKFNFFANAEASFYQGSQSGDKFDRLPFMNRGRGADVLDALPHSSGSG 291
            ...| |..:.::|..|       |.|.|:......|..:..:.|              |:..||.
Mouse   207 QTSH-PGKMQEAAAVA-------AAAAAAAAAAVGSVGRLSQFP--------------PYGLGSA 249

  Fly   292 GGVGGGSESSRGSKYKSPYAFDVATVASAAGIPGHRDYAERLSAGG 337
            ......:.:|. :.:|.|:|.:        .|.| |||...|.|||
Mouse   250 AAAAAAAAAST-TGFKHPFAIE--------NIIG-RDYKGVLQAGG 285

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
fd59ANP_523814.1 Forkhead 85..171 CDD:278670 54/85 (64%)
Foxb2NP_032049.1 FH 13..101 CDD:214627 55/87 (63%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 118..217 15/100 (15%)
E_Pc_C <342..>406 CDD:284226
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 408..428
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 1 1.000 - - FOG0000010
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 1 1.030 - avgDist Average_Evolutionary_Distance R2114
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
32.940

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