DRSC/TRiP Functional Genomics Resources

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Protein Alignment fd59A and Foxh1

DIOPT Version :9

Sequence 1:NP_523814.1 Gene:fd59A / 37631 FlyBaseID:FBgn0004896 Length:456 Species:Drosophila melanogaster
Sequence 2:NP_032015.1 Gene:Foxh1 / 14106 MGIID:1347465 Length:401 Species:Mus musculus


Alignment Length:150 Identity:51/150 - (34%)
Similarity:81/150 - (54%) Gaps:20/150 - (13%)


- Green bases have known domain annotations that are detailed below.


  Fly    85 KPPYSYIALITMAILQSPHKKLTLSGICDFIMSRFPYYKDKFPAWQNSIRHNLSLNDCFIKVPRE 149
            ||||:|:|:|.:.|..:|.::|.|:.|...:.:.||:::|.:..|::|||||||.|.||.|||::
Mouse    64 KPPYTYLAMIALVIQAAPFRRLKLAQIIRQVQAVFPFFRDDYEGWKDSIRHNLSSNRCFHKVPKD 128

  Fly   150 PGNP-GKGNFWTLD----PLAEDMFDNGSFLRRRKRYKRAPTMQRFSFPAVFGTLSPFWI----- 204
            |..| .|||||.:|    |.......|.:..|   |::...|.:.|:     ..|||:.:     
Mouse   129 PAKPQAKGNFWAVDVSLIPAEALRLQNTALCR---RWQNRGTHRAFA-----KDLSPYVLHGQPY 185

  Fly   205 RKPVPLVPVH--FNVPNFNG 222
            :.|.|..|..  |::.:..|
Mouse   186 QPPSPPPPPREGFSIKSLLG 205

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
fd59ANP_523814.1 Forkhead 85..171 CDD:278670 38/90 (42%)
Foxh1NP_032015.1 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 32..57
FH 64..142 CDD:238016 36/77 (47%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 179..251 4/26 (15%)
SMAD-interaction domain (SID) 307..390
Fast/FoxH1 motif 1 (FM1) 311..315
Fast/FoxH1 motif 2 (FM2) 321..327
SMAD interaction motif (SIM) 363..384
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E2759_KOG2294
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 1 1.010 - - D1270467at2759
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
21.910

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