DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment fd59A and foxk2

DIOPT Version :9

Sequence 1:	NP_523814.1	Gene:	fd59A / 37631	FlyBaseID:	FBgn0004896	Length:	456	Species:	Drosophila melanogaster
Sequence 2:	NP_001135634.1	Gene:	foxk2 / 100216193	XenbaseID:	XB-GENE-483520	Length:	645	Species:	Xenopus tropicalis

Alignment Length:	208	Identity:	78/208 - (37%)
Similarity:	99/208 - (47%)	Gaps:	19/208 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly    17 LSPPLIKSSRGGSSIGNGIGCSASSRTAAADAMSMGCDDSDIEPSSMGGSGAAGGNGDGS-GSSG 80
            :||  :.|..|..|..|  .|.:|.|.|.:....:|   ..|.|..:..:..:..:.|.| |.|.
Frog   157 ISP--LPSPTGTISAAN--SCPSSPRGAGSSGFKLG---RVIPPDLIAEAAQSENDKDASGGDSP 214

  Fly    81 GPLVKPPYSYIALITMAILQSPHKKLTLSGICDFIMSRFPYYKDKFPAWQNSIRHNLSLNDCFIK 145
            ....||||||..||..||..:|.|:|||:||...|...:|||:.....||||||||||||..|||
Frog   215 KDDSKPPYSYAQLIVQAITMAPDKQLTLNGIYTHITKNYPYYRTADKGWQNSIRHNLSLNRYFIK 279

  Fly   146 VPREPGNPGKGNFWTLDPLAEDMFDNGSFLRRRKRYKRAPTMQRFSFPAVFGTLSPFWIRKPVPL 210
            |||....||||:||.:||.:|......:|.:||.|          ..|.....|.|...|. .|.
Frog   280 VPRSQEEPGKGSFWRIDPASESKLVEQAFRKRRPR----------GVPCFRTPLGPLSSRS-APA 333

  Fly   211 VPVHFNVPNFNGS 223
            .|.|..|.:.:.|
Frog   334 SPNHAGVLSAHSS 346

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
fd59A	NP_523814.1	Forkhead	85..171	CDD:278670	48/85 (56%)
foxk2	NP_001135634.1	FHA	10..117	CDD:238017
foxk2	NP_001135634.1	Forkhead	218..304	CDD:365978	48/85 (56%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1270467at2759
OrthoFinder	1	1.000	-	-		FOG0000010
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2114
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	3.040