DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment fd59A and foxl2b

DIOPT Version :9

Sequence 1:	NP_523814.1	Gene:	fd59A / 37631	FlyBaseID:	FBgn0004896	Length:	456	Species:	Drosophila melanogaster
Sequence 2:	NP_001304690.1	Gene:	foxl2b / 100149117	ZFINID:	ZDB-GENE-170803-1	Length:	285	Species:	Danio rerio

Alignment Length:	364	Identity:	109/364 - (29%)
Similarity:	146/364 - (40%)	Gaps:	112/364 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly    39 ASSRTAAADAMSMGCDDSDI-----EPSSMGGSGAAGGNGDGSGSSGGPLVKPPYSYIALITMAI 98
            ||..:...|||::...|::.     ||....||           ....|..||||||:|||.|||
Zfish     2 ASYHSLDDDAMALMVHDTNAVKKEDEPLQEPGS-----------EKTDPAQKPPYSYVALIAMAI 55

  Fly    99 LQSPHKKLTLSGICDFIMSRFPYYKDKFPAWQNSIRHNLSLNDCFIKVPREPGNPGKGNFWTLDP 163
            .:|..|:||||||..:|:::||:|:.....||||||||||||:||||||||.|...|||:|||||
Zfish    56 RESTEKRLTLSGIYQYIITKFPFYEKNKKGWQNSIRHNLSLNECFIKVPREGGGERKGNYWTLDP 120

  Fly   164 LAEDMFDNGSFLRRRKRYKRAPTMQRFSFPAVFGTLSPFWIRKPVPLVPVHFNVPN--FNGSREF 226
            ..||||:.|:: |||:|.||                 ||  |.|.    .||....  |.|
Zfish   121 ACEDMFEKGNY-RRRRRMKR-----------------PF--RPPA----AHFQAGKSLFGG---- 157

  Fly   227 DVVHNPADVFDSALRADKKF-NFFANAE---------ASFYQGSQ---------------SGDKF 266
                   |.:...|.|.|.. :.|.|:.         |..|...|               |.:.:
Zfish   158 -------DAYTGYLPAPKYLQSGFMNSSWPLPQPPPPAMSYASCQMPNGNMGAMKALSTPSYNPY 215

  Fly   267 DRLPFMNRGRGADVLDALPHSSGSGGGVGGGSESSRGSKYKSPYAFDVATVASAAGIPGHRDYAE 331
            .|:..|          .||:...|.||:|...:                        |.|:..:.
Zfish   216 SRMQAM----------GLPNMMNSYGGMGHHQQ------------------------PQHQQQSA 246

  Fly   332 RLSAGGGYMDLNVYNDDADTEADAEAEGDDDSCEDKIDV 370
            ..|.....:........|:..:..|.|....:...:||:
Zfish   247 APSNSAAALQFTCSRQPAELYSYWEHEAKSSALHSRIDI 285

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
fd59A	NP_523814.1	Forkhead	85..171	CDD:278670	57/85 (67%)
foxl2b	NP_001304690.1	FH	42..130	CDD:214627	57/87 (66%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG2294
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1270467at2759
OrthoFinder	1	1.000	-	-		FOG0000010
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	4	3.820