DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment fd59A and foxg1

DIOPT Version :9

Sequence 1:	NP_523814.1	Gene:	fd59A / 37631	FlyBaseID:	FBgn0004896	Length:	456	Species:	Drosophila melanogaster
Sequence 2:	NP_001116933.1	Gene:	foxg1 / 100144706	XenbaseID:	XB-GENE-480076	Length:	432	Species:	Xenopus tropicalis

Alignment Length:	332	Identity:	112/332 - (33%)
Similarity:	148/332 - (44%)	Gaps:	65/332 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 PMH-TLHDSVSLSPPLIKSSRGGSSIGNGIGCSASSRTAAADAMSMGCDDSDIEPSSMGGSGAAG 70
            |.| .|.:...|...|::...  .|:..|.|..|:|.....|      .:...:..:.||.|..|
Frog    52 PHHRPLQEEDELDKSLLEVKT--ESLPPGKGDPAASELPGED------KEKSEDKKADGGGGKDG 108

  Fly    71 GNG-DGSGSSGGPLVKPPYSYIALITMAILQSPHKKLTLSGICDFIMSRFPYYKDKFPAWQNSIR 134
            .|| :|.....|...|||:||.|||.|||.|||.|:|||:||.:|||..||||::....||||||
Frog   109 ENGKEGGEKKNGKYEKPPFSYNALIMMAIRQSPEKRLTLNGIYEFIMKNFPYYRENKQGWQNSIR 173

  Fly   135 HNLSLNDCFIKVPREPGNPGKGNFWTLDPLAEDMFDNGSF--LRRRKRYKRAP---------TMQ 188
            ||||||.||:||||...:|||||:|.|||.::|:|..|:.  ||||....||.         |..
Frog   174 HNLSLNKCFVKVPRHYDDPGKGNYWMLDPSSDDVFIGGTTGKLRRRSTTSRAKLAFKRGARLTST 238

  Fly   189 RFSFPAVFGTLSPFWIRKPVPLVPVHFNVPNFNGSREFDVVHNPADVFDSALRADKKFNFFANAE 253
            ..:|....|:|  :|     |:.|             |..:|:|        ||         :.
Frog   239 GLTFMDRAGSL--YW-----PMSP-------------FLSLHHP--------RA---------SS 266

  Fly   254 ASFYQGSQSGDKFDRLPFMNRGRGADVLDALPHSSGSGGGVGGGSESSRGSKYKSPYAFDVATVA 318
            |..|.|:.|......:|:      :.||......|........|....|....:.|||....|.|
Frog   267 ALSYNGTTSAYPSHPMPY------SSVLTQNSLGSNHSFSTSNGLSVDRLVNGEIPYATHHLTAA 325

  Fly   319 S-AAGIP 324
            : ||.:|
Frog   326 ALAASVP 332

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
fd59A	NP_523814.1	Forkhead	85..171	CDD:278670	56/85 (66%)
foxg1	NP_001116933.1	FH	124..212	CDD:214627	56/87 (64%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1270467at2759
OrthoFinder	1	1.000	-	-		FOG0000010
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.920