DRSC/TRiP Functional Genomics Resources

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Protein Alignment inaD and CYTIP

DIOPT Version :9

Sequence 1:NP_001246470.1 Gene:inaD / 37629 FlyBaseID:FBgn0001263 Length:686 Species:Drosophila melanogaster
Sequence 2:NP_004279.3 Gene:CYTIP / 9595 HGNCID:9506 Length:359 Species:Homo sapiens


Alignment Length:240 Identity:52/240 - (21%)
Similarity:87/240 - (36%) Gaps:48/240 - (20%)


- Green bases have known domain annotations that are detailed below.


  Fly    29 MVTLDKTGKKSFGICI--VRGEVKDSPNTKTTGIFIKGIVPDSPAHLCGRLKVGDRILSLNGKDV 91
            :||::|...::||..|  .|.:.:::.:::...:..| |..||||| |..|:.||.:.::||...
Human    77 LVTVEKQDNETFGFEIQSYRPQNQNACSSEMFTLICK-IQEDSPAH-CAGLQAGDVLANINGVST 139

  Fly    92 RNSTEQAVIDLIKEADFKIELEIQTFD-----KSDEQQAKSDPRSNGYMQAKNKFNQEQTTNNNA 151
            ...|.:.|:|||:.:...  |.|:|.:     |..|.:||.........|...::...|...:..
Human   140 EGFTYKQVVDLIRSSGNL--LTIETLNGTMILKRTELEAKLQVLKQTLKQKWVEYRSLQLQEHRL 202

  Fly   152 SGGQG----------------MGQGQGQGQGMAGMNRQQSMQKRNTTFTA--------------- 185
            ..|..                .|...|.|..:...||..|.....:..::               
Human   203 LHGDAANCPSLENMDLDELSLFGPLPGPGPALVDRNRLSSESSCKSWLSSMTMDSEDGYQTCVSE 267

  Fly   186 -SMRQKHSNYADEDDE-----DTRDMTGRIRTEAGYEIDRASAGN 224
             |.|...|.....|||     :..|...|..:.....|...|:|:
Human   268 DSSRGAFSRQTSTDDECFIPKEGDDFLRRSSSRRNRSISNTSSGS 312

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
inaDNP_001246470.1 PDZ_signaling 27..115 CDD:238492 26/87 (30%)
PDZ_signaling 259..340 CDD:238492
PDZ_signaling 377..457 CDD:238492
PDZ_signaling 500..584 CDD:238492
PDZ_signaling 597..672 CDD:238492
CYTIPNP_004279.3 PDZ_signaling 76..161 CDD:238492 26/87 (30%)
Interaction with CYTH1 166..188 4/21 (19%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG3528
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
10.900

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