Protein Alignment inaD and Pard3

DIOPT Version :9

• Sequence 1: NP_001246470.1
• Gene: inaD / 37629
• FlyBaseID: FBgn0001263
• Length: 686
• Species: Drosophila melanogaster
• Sequence 2: XP_006531583.1
• Gene: Pard3 / 93742
• MGIID: 2135608
• Length: 1337
• Species: Mus musculus
• Alignment Length: 552
• Identity: 111/552 - (20%)
• Similarity: 195/552 - (35%)
• Gaps: 143/552 - (25%)

  Fly   127 SDPRSNGYMQ--AKNKFNQEQTTNNNASGGQGMGQGQGQGQGMAGMNRQQSMQKRNTTFTASMRQ 189
            |||...|...  :.|.|:.|:.:..|.:          :....||..:|.:.....|    ..|:
Mouse   144 SDPALTGLSTSVSDNNFSSEEPSRKNPT----------RWSTTAGFLKQNTAGSPKT----CDRK 194

  Fly   190 KHSNY-------ADEDDEDTRDMTGRIRTEAGYE-IDRASAGNCKLNKQEKDRDKEQEDE----- 241
            |..||       :...::..|| ..|....|.:. :||      .|.|||:|.:..:||.
Mouse   195 KDENYRSLPRDPSSWSNQFQRD-NARSSLSASHPMVDR------WLEKQEQDEEGTEEDSSRVEP 252

  Fly   242 FGYTMAKINKRYNMMKD--LRRIEVQRDASKPLGLALAGHKDR--QKMACFVAGVDPNGALGSVD 302
            .|:....:....|...|  ::.::|..|.. |||:.:.....|  :.:...|..::..|.....:
Mouse   253 VGHADTGLENMPNFSLDDMVKLVQVPNDGG-PLGIHVVPFSARGGRTLGLLVKRLEKGGKAEQEN 316

  Fly   303 I-KPGDEIVEVNGNVLKNRCHLNASAVFKN--------------VDGDKLVMITSRRKPN----- 347
            : ...|.||.:|...|:||....|..:|:.              .:.::...::.|.|.|
Mouse   317 LFHENDCIVRINDGDLRNRRFEQAQHMFRQAMRARVIWFHVVPAANKEQYEQLSQREKNNYSPGR 381

  Fly   348 --DEGMCV----------KPIKKFPTASDETKFIFDQFP-------------------------- 374
              .:..||          :.:.:.|..|...:.: |..|
Mouse   382 FSPDSHCVANRSVANNAPQALPRAPRLSQPPEQL-DAHPRLPHSAHASTKPPAAPALAPPSVLST 445

  Fly   375 ------------KARTVQVRK--EGFLGIMVIYGKHAEVGSG--IFISD-LREGSNAELAGVKVG 422
                        |...:|::|  || ||.. |..:...:|..  |::.: |..|:..:...:|.|
Mouse   446 NVGSVYNTKKVGKRLNIQLKKGTEG-LGFS-ITSRDVTIGGSAPIYVKNILPRGAAIQDGRLKAG 508

  Fly   423 DMLLAVNQDVTLESNYDDATGLLKRAEGVVTMILLTLKSEEA-----IKAEKAAEEKKKEEAKKE 482
            |.|:.||.......:.::...||:..:...|:.||..:.|||     :.||.:..:..||...::
Mouse   509 DRLIEVNGVDLAGKSQEEVVSLLRSTKMEGTVSLLVFRQEEAFHPREMNAEPSQMQTPKETKAED 573

  Fly   483 EEKPQEP------ATAEIKPNKKILIELKVEKKPMGVIVCG--GKNNHVTTGCVITHVYPEGQVA 539
            |:....|      .|.|:..|..       ....:||.|.|  .|.||...|..:..:...|..:
Mouse   574 EDVVLTPDGTREFLTFEVPLNDS-------GSAGLGVSVKGNRSKENHADLGIFVKSIINGGAAS 631

  Fly   540 ADKRLKIFDHICDINGTPI----HVGSMTTLK 567
            .|.||::.|.:..:||..:    :..:|.||:
Mouse   632 KDGRLRVNDQLIAVNGESLLGKANQEAMETLR 663

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
inaD	NP_001246470.1	PDZ_signaling	27..115	CDD:238492
		PDZ_signaling	259..340	CDD:238492	17/97 (18%)
		PDZ_signaling	377..457	CDD:238492	20/84 (24%)
		PDZ_signaling	500..584	CDD:238492	18/74 (24%)
		PDZ_signaling	597..672	CDD:238492
Pard3	XP_006531583.1	DUF3534	2..83	CDD:338230
		PDZ_signaling	272..347	CDD:238492	17/75 (23%)
		PDZ_signaling	465..544	CDD:238492	20/80 (25%)
		PDZ_signaling	588..681	CDD:238492	21/83 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3528
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900