DRSC/TRiP Functional Genomics Resources

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Protein Alignment inaD and PDZD7

DIOPT Version :9

Sequence 1:NP_001246470.1 Gene:inaD / 37629 FlyBaseID:FBgn0001263 Length:686 Species:Drosophila melanogaster
Sequence 2:NP_001182192.1 Gene:PDZD7 / 79955 HGNCID:26257 Length:1033 Species:Homo sapiens


Alignment Length:305 Identity:72/305 - (23%)
Similarity:118/305 - (38%) Gaps:77/305 - (25%)


- Green bases have known domain annotations that are detailed below.


  Fly   207 GRIRTEAGYEIDRASAGNCKLNKQEK-----DRDKEQEDEFGYTMAKINKRYNMMKD----LRRI 262
            |.:.:::|     ::|....|.||::     .|........|..:. ||.......|    :..:
Human    29 GHLGSDSG-----STATRYLLRKQQRLLNGPPRGIRASSPMGRVIL-INSPIEANSDESDIIHSV 87

  Fly   263 EVQRDASKPLGLALAGHKDRQKMACFVAGVDPNGALGSVDIKPGDEIVEVNGNVLK--------- 318
            .|::..:..||.::.|..: ..:..||:.|:...:.....:..||:|.||||..|:         
Human    88 RVEKSPAGRLGFSVRGGSE-HGLGIFVSKVEEGSSAERAGLCVGDKITEVNGLSLESTTMGSAVK 151

  Fly   319 -----NRCHLNASAVFKNVDGDKL-------VMITSRR--------KPND----EGMCVKPIKKF 359
                 :|.|:....:.: |.|.|.       |.:.:||        .|:|    :|  |:.|...
Human   152 VLTSSSRLHMMVRRMGR-VPGIKFSKEKTTWVDVVNRRLVVEKCGSTPSDTSSEDG--VRRIVHL 213

  Fly   360 PTASDETKFIFDQFPKARTVQVRKEGFLGIMVIYGKHAEVGSGIFISDLREGSNAELAGVKVGDM 424
            .|.||:.                   .||..:..||  |.|.||::|.:..|..||..|:||||.
Human   214 YTTSDDF-------------------CLGFNIRGGK--EFGLGIYVSKVDHGGLAEENGIKVGDQ 257

  Fly   425 LLAVNQDVTLESNYDDATGLLKRAEGVVTMILLTLKSEEAIKAEK 469
            :||.|.....:.::..|..:||..    |.|:||:|......|.|
Human   258 VLAANGVRFDDISHSQAVEVLKGQ----THIMLTIKETGRYPAYK 298

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
inaDNP_001246470.1 PDZ_signaling 27..115 CDD:238492
PDZ_signaling 259..340 CDD:238492 21/101 (21%)
PDZ_signaling 377..457 CDD:238492 25/79 (32%)
PDZ_signaling 500..584 CDD:238492
PDZ_signaling 597..672 CDD:238492
PDZD7NP_001182192.1 PDZ_signaling 84..164 CDD:238492 17/80 (21%)
PDZ_signaling 209..289 CDD:238492 31/104 (30%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 323..380
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 444..464
HN_PDZD7_like 554..630 CDD:259824
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 754..864
PDZ_signaling 860..948 CDD:238492
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 943..1033
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG3528
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
21.810

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