DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment inaD and GOPC

DIOPT Version :9

Sequence 1:	NP_001246470.1	Gene:	inaD / 37629	FlyBaseID:	FBgn0001263	Length:	686	Species:	Drosophila melanogaster
Sequence 2:	NP_065132.1	Gene:	GOPC / 57120	HGNCID:	17643	Length:	462	Species:	Homo sapiens

Alignment Length:	157	Identity:	39/157 - (24%)
Similarity:	68/157 - (43%)	Gaps:	33/157 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly    27 IHMVTLDKTGKKSFGICIVRGEVKDSPNTKTTGIFIKGIVPDSPAHLCGRLKVGDRILSLNGKDV 91
            |..|.|.|...:..||.|..|:....|      |.|..|.|..||..||.|.|||.||::||.::
Human   286 IRKVLLLKEDHEGLGISITGGKEHGVP------ILISEIHPGQPADRCGGLHVGDAILAVNGVNL 344

  Fly    92 RNSTEQAVIDLIKEADFKIEL-------EIQTFDKSDEQQAKSDPR------------------- 130
            |::..:..:.::.:...:||.       |:.:.|::.|.:.:|..|
Human   345 RDTKHKEAVTILSQQRGEIEFEVVYVAPEVDSDDENVEYEDESGHRYRLYLDELEGGGNPGASCK 409

  Fly   131 -SNGYMQAKNKFNQEQTTNNNASGGQG 156
             ::|.::....||::..|:.:.:|..|
Human   410 DTSGEIKVLQGFNKKAVTDTHENGDLG 436

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
inaD	NP_001246470.1	PDZ_signaling	27..115	CDD:238492	29/94 (31%)
		PDZ_signaling	259..340	CDD:238492
		PDZ_signaling	377..457	CDD:238492
		PDZ_signaling	500..584	CDD:238492
		PDZ_signaling	597..672	CDD:238492
GOPC	NP_065132.1	bZIP_2	<166..199	CDD:285017
		PDZ_signaling	286..368	CDD:238492	28/87 (32%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	426..449		3/11 (27%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3528
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810