Protein Alignment inaD and lnx2b

DIOPT Version :9

• Sequence 1: NP_001246470.1
• Gene: inaD / 37629
• FlyBaseID: FBgn0001263
• Length: 686
• Species: Drosophila melanogaster
• Sequence 2: NP_998105.2
• Gene: lnx2b / 564464
• ZFINID: ZDB-GENE-040426-2500
• Length: 678
• Species: Danio rerio
• Alignment Length: 559
• Identity: 122/559 - (21%)
• Similarity: 206/559 - (36%)
• Gaps: 120/559 - (21%)

  Fly   208 RIRTEAGYEIDRASAGNCKLNKQEKD-RDKEQEDEFGYTMAKINK-------------------- 251
            |:|.||..: .|.|....|.:|.:.| .|.:.....|.| |:::.
Zfish   138 RLREEAERK-KRPSWNELKGSKSDGDLADAKSAQTIGRT-AQLSAPSEPGLVNPAFEEGEDDTPL 200

  Fly   252 RYNMMKDLRRIEVQR-DASKPLGLALAGHKDRQKMACFVAGVDPNGALGSVDIK----------- 304
            |.:::.:...:|:.| |..:.|||.:.|.||.              .||::.|:
Zfish   201 RCSLVAEATVVELFREDPGEDLGLRIVGGKDT--------------PLGNIVIQEIVRDSLVARD 251

  Fly   305 ----PGDEIVEVNGNVLKNRCHLNASAVFKNVDGDKLVMITSRR--KPNDEGMCVKPIKKFPTAS 363
                |||.|:|||...|.:..|..|.||.:.......:.:...:  ||..|.. .:|....||.|
Zfish   252 GKLAPGDHILEVNDVSLASISHSRAIAVIRQPCSRLRLTVMQEKGFKPRPEHH-TQPSASPPTQS 315

  Fly   364 DETKFIFDQFPKARTVQVRKEGFLGIMVIYGKHAEVGSGIFISDLREGSNAELAG-VKVGDMLLA 427
            ..|........:...|:..:...|||.:| .|..|  .|:||.||..|..|...| ::..|.:|.
Zfish   316 PSTNQNHGTVIQVTLVKHERSEALGIKLI-RKSEE--PGVFILDLLPGGLAAKDGKLRNNDKVLG 377

  Fly   428 VNQDVTLESNYDDATGLLKRAEGVVTMILLTLK--SEEAIKAEKAAEEKKKEEA--KKEEEKPQE 488
            :|.........:.|..:::.:|..|..:::.|:  |||..:.:.....:..|..  ::..|..:|
Zfish   378 INGQDLRHGTPESAAQIIQASEMRVNFVVMRLQDVSEEGGEGQSRGARRVPEPQYFRRHSEYMKE 442

  Fly   489 PATAEIKPNKKILIELKVEKKPMGVIVCGGKNNHVTTGCVITHVYPEGQVAADKRLKIFDHICDI 553
            |........|.:.:: |..::.:|:.:.||::........||.|.|.|.:..|..:|..|.:..|
Zfish   443 PPGGFSSQEKTVTLK-KEPRQSLGITIAGGRDCRSRLPVYITSVQPVGCLHRDGTVKTGDVLLSI 506

  Fly   554 NGTPI-HV---GSMTTLKVHQLFHTTYEKAVTLTVFRA--------------------DPPELEK 594
            ||..: |:   .::|.||..     |.:..|||.|.:.                    :.|:.:.
Zfish   507 NGIDLTHLTYNEAVTVLKTQ-----TAQSTVTLRVIQTFADDEEQDGESGSREDMDTMEGPKDDD 566

  Fly   595 FN--------------------VDLMKKAGKELGLSL------SPNEIGCTIADLIQGQYPEIDS 633
            .|                    :.|||...:..|.|:      |..:....|..::.|.....|.
Zfish   567 INWVPLWTRWLGLPSCIHWCRDIMLMKTNSESWGFSIVGGYEESRGQQPFFIKTIVPGTPAYFDG 631

  Fly   634 KLQRGDIITKFNGDALEGLPFQVCYALFKGANGKVSMEV 672
            :|:.||.|...||....|:.......:.|....||::.|
Zfish   632 RLKCGDEIVAVNGVTTVGMNNSSLIPMLKLQKNKVTLTV 670

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
inaD	NP_001246470.1	PDZ_signaling	27..115	CDD:238492
		PDZ_signaling	259..340	CDD:238492	24/96 (25%)
		PDZ_signaling	377..457	CDD:238492	21/80 (26%)
		PDZ_signaling	500..584	CDD:238492	23/87 (26%)
		PDZ_signaling	597..672	CDD:238492	19/80 (24%)
lnx2b	NP_998105.2	RING	46..82	CDD:214546
		PDZ_signaling	210..291	CDD:238492	24/94 (26%)
		PDZ_signaling	325..406	CDD:238492	21/83 (25%)
		PDZ_signaling	451..537	CDD:238492	24/91 (26%)
		PDZ_signaling	587..671	CDD:238492	20/84 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3528
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR19964
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	4	3.870