DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment inaD and PDZD11

DIOPT Version :9

Sequence 1:	NP_001246470.1	Gene:	inaD / 37629	FlyBaseID:	FBgn0001263	Length:	686	Species:	Drosophila melanogaster
Sequence 2:	XP_016885057.1	Gene:	PDZD11 / 51248	HGNCID:	28034	Length:	172	Species:	Homo sapiens

Alignment Length:	95	Identity:	27/95 - (28%)
Similarity:	48/95 - (50%)	Gaps:	8/95 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly    30 VTLDKTGKKSFGICIVRGEVKDSPNTKTTGIFIKGIVPDSPAHLCGRLKVGDRILSLNGKDVRNS 94
            :||.|......|..|..|:...      .||||..::|||.||..| |:.||::|::|..|.::.
Human    80 ITLKKPPGAQLGFNIRGGKASQ------LGIFISKVIPDSDAHRAG-LQEGDQVLAVNDVDFQDI 137

  Fly    95 TEQAVIDLIKEADFKIELEIQTFDKSDEQQ 124
            .....::::|.|. :|.:.::.|..:..:|
Human   138 EHSKAVEILKTAR-EISMRVRFFPYNYHRQ 166

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
inaD	NP_001246470.1	PDZ_signaling	27..115	CDD:238492	25/84 (30%)
		PDZ_signaling	259..340	CDD:238492
		PDZ_signaling	377..457	CDD:238492
		PDZ_signaling	500..584	CDD:238492
		PDZ_signaling	597..672	CDD:238492
PDZD11	XP_016885057.1	PDZ_signaling	77..157	CDD:238492	25/84 (30%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3528
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810