Protein Alignment inaD and Pdzd3

DIOPT Version :9

• Sequence 1: NP_001246470.1
• Gene: inaD / 37629
• FlyBaseID: FBgn0001263
• Length: 686
• Species: Drosophila melanogaster
• Sequence 2: NP_001178925.1
• Gene: Pdzd3 / 500986
• RGDID: 1559807
• Length: 498
• Species: Rattus norvegicus
• Alignment Length: 600
• Identity: 121/600 - (20%)
• Similarity: 201/600 - (33%)
• Gaps: 192/600 - (32%)

  Fly    76 RLKVGDRILSL----NGKDVRNSTEQAVIDLIKEAD--FKIELEIQTFDKSDEQQAKSDPRSNGY 134
            ||.:.:.:|||    :..|..|........|.||.:  |...|: |...|:|....:.||.|:..
  Rat    22 RLGIDNPVLSLAEDQDQSDPWNLHRPRFCLLSKEEEKSFGFHLQ-QQLGKADHVVCRVDPGSSAQ 85

  Fly   135 MQAKNKFNQEQTTNNNASGGQGMGQGQGQGQGMAGMNRQQSMQKRNTTFTASMRQKHSNYADEDD 199
            .|...:.::....|||.                                     .:|.:||
  Rat    86 RQGLREGDRILAVNNNI-------------------------------------VEHEDYA---- 109

  Fly   200 EDTRDMTGRIRTEAG------------YEIDRASAGN----C---------KLNKQEKDRDKEQE 239
                 :..|....:|            |::.||..||    |         :|....||     |
  Rat   110 -----VVVRYIRASGPRVLLTVLAQHVYDVTRAQQGNEAFPCPTLASGVRPRLCHVVKD-----E 164

  Fly   240 DEFGYTMAKINKRYNMMKDLRRIEVQRDASKPLGLALAGHKDRQKMACFVAGVDPNGALGSVDIK 304
            ..||::                  |...|..|..|.|:            ||    ||.....:.
  Rat   165 GGFGFS------------------VTHGARGPFWLVLS------------AG----GAAERAGVP 195

  Fly   305 PGDEIVEVNG--------NVLKNR-CHLNASAVFKNVDGDKLVMITSRRKPNDEGMCVK---PIK 357
            ||..::||||        |.|..: |.          .||::.::.:  .|..|..|.:   |:.
  Rat   196 PGARLLEVNGICVEKFTYNQLNRKLCQ----------SGDRVTLLVA--GPEVEEQCHQLGMPLA 248

  Fly   358 KFPTASDETKFIFDQFPKARTVQVRKEGFLGIMVIYGKHAEVGSGIFISDLREGSNAELAGVKVG 422
            . |.|..   :.....|:...::...:|| |.::...|..:...|.|:.::..|..|:.||:|.|
  Rat   249 A-PLAEG---WALPAKPRCLNIEKGPQGF-GFLLREEKGPDGRLGQFLWEVDPGLPADKAGMKAG 308

  Fly   423 DMLLAVNQDVTLESNYDDATGLLKRAEGVVTMILLTLKSEEAIKAEKAAEEKKKEEAKKEEEKPQ 487
            |.|:||..:......:::....::.....|:::::..:::......:.:.....|..
  Rat   309 DRLVAVAGESMDGLGHEETVSRIRAQGSCVSLVVVDPEADRFFSMVRLSPLLFLENT-------- 365

  Fly   488 EPATAEIKPNKKILIELKVEKKPMGVIVCGGKNNHVTTG----------CV-------ITHVYPE 535
            |.|.|.:...|.:.:|..||  |.|  :.|.:...:..|          ||       |:.|.|.
  Rat   366 EIAAAPLAETKDLPVEDTVE--PSG--LAGSRQCFLYPGPGGGYGFRLRCVASGPCLFISQVTPG 426

  Fly   536 GQVAADKRLKIFDHICDINGTPIHVGSMTTLKVHQLFHTTYEKAVTLTVFRADPPELEKFNVDLM 600
            |. ||...|::.|.|.::||.|  ||..:.|...|            .:..|:||  .:..:...
  Rat   427 GS-AARAGLQMGDAILEVNGCP--VGGDSDLDTLQ------------QLAEAEPP--LRLKLAPR 474

  Fly   601 KKAGKELGLSLSPNE 615
            ...|.|..:||...|
  Rat   475 NSQGSEAWISLESGE 489

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
inaD	NP_001246470.1	PDZ_signaling	27..115	CDD:238492	12/44 (27%)
		PDZ_signaling	259..340	CDD:238492	20/89 (22%)
		PDZ_signaling	377..457	CDD:238492	17/79 (22%)
		PDZ_signaling	500..584	CDD:238492	25/100 (25%)
		PDZ_signaling	597..672	CDD:238492	4/18 (22%)
Pdzd3	NP_001178925.1	PDZ_signaling	47..127	CDD:238492	20/126 (16%)
		PDZ_signaling	155..232	CDD:238492	26/125 (21%)
		PDZ	260..345	CDD:214570	18/85 (21%)
		PDZ_signaling	407..472	CDD:238492	21/81 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3528
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900