DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment inaD and CG34375

DIOPT Version :9

Sequence 1:	NP_001246470.1	Gene:	inaD / 37629	FlyBaseID:	FBgn0001263	Length:	686	Species:	Drosophila melanogaster
Sequence 2:	NP_001163693.1	Gene:	CG34375 / 42715	FlyBaseID:	FBgn0085404	Length:	568	Species:	Drosophila melanogaster

Alignment Length:	170	Identity:	34/170 - (20%)
Similarity:	59/170 - (34%)	Gaps:	66/170 - (38%)

- Green bases have known domain annotations that are detailed below.

  Fly     9 GTAGVFISFGMHNPFPELIHMVTLDKTGKKSFGICIVRGEVKDSPNTKTTGIFIKGIVPDSPAHL 73
            ||.|:.:|....:|:|                                    ::.|:...|.|..
  Fly    13 GTLGLNLSRAPWDPYP------------------------------------WVSGVQAKSSAER 41

  Fly    74 CGRLKVGDRILSLNGKDVRNSTEQAVIDLIKEADFKIELEIQTFDKSDEQQAKSDPRSNGYMQAK 138
             |.:::||.:|.|||.||.......:.:.::: .::...|:.|. ....|||..||
  Fly    42 -GGVRLGDTLLELNGADVLGLKISELANRLQD-HWQSGAEVVTL-MMWRQQANIDP--------- 94

  Fly   139 NKFNQEQTTNNNASGGQGMGQGQGQGQGMAGMNRQQSMQK 178
               |::....::|.              ..|:| |||:||
  Fly    95 ---NEDPAEASHAV--------------QHGIN-QQSLQK 116

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
inaD	NP_001246470.1	PDZ_signaling	27..115	CDD:238492	13/87 (15%)
		PDZ_signaling	259..340	CDD:238492
		PDZ_signaling	377..457	CDD:238492
		PDZ_signaling	500..584	CDD:238492
		PDZ_signaling	597..672	CDD:238492
CG34375	NP_001163693.1	PDZ	13..86	CDD:238080	20/111 (18%)
CG34375	NP_001163693.1	RING	129..168	CDD:238093
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3528
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.900