Protein Alignment inaD and dysc

DIOPT Version :9

• Sequence 1: NP_001246470.1
• Gene: inaD / 37629
• FlyBaseID: FBgn0001263
• Length: 686
• Species: Drosophila melanogaster
• Sequence 2: NP_001261810.1
• Gene: dysc / 39533
• FlyBaseID: FBgn0264006
• Length: 1254
• Species: Drosophila melanogaster
• Alignment Length: 597
• Identity: 111/597 - (18%)
• Similarity: 213/597 - (35%)
• Gaps: 169/597 - (28%)

  Fly   130 RSNGYMQAKNKFNQEQTT-----NNNASGGQGMGQ-GQGQGQGMAGMNRQQSMQKRNTTFTASMR 188
            |.:.|:.:....:....|     .:.|:.|:.||| ....|.....::.:|.::....|.::|:.
  Fly   177 RGSAYLSSSPASHMAAGTAGTLPTSTAASGRSMGQHASSNGNKKRPISPEQVLRMFGATQSSSVP 241

  Fly   189 QKHSNYADEDDEDTRDMTGRIRTEAGYEIDRASAGNCKLNKQEKDRDKEQEDEFGYTMAKINKRY 253
            ....:|::....| ||.|||          |:.|.:......:..||:|:|.:  .::..|::
  Fly   242 TSSYHYSNGGTRD-RDRTGR----------RSPASSPPSTTHQIYRDRERERD--RSVPNIHE-- 291

  Fly   254 NMMKDLRRIEVQRD--ASKPLGLALAGHKDRQKMACFVAGVDPNGALGSVDIKPGDEIVEVNGNV 316
               ...|.:.:.||  .....|:.:.|.|| ..:..:::.::.|.......::|||.|:||||..
  Fly   292 ---LTTRTVSMSRDQQIDHGFGICVKGGKD-SGLGVYISRIEENSVAERAGLRPGDTILEVNGTP 352

  Fly   317 LKNRCHLNA-SAVFKNVDGDKLVMITSRRKPNDEGMCVKPIKKFPTASDETKFI----------- 369
            ..:..|..| ....:.:...:.:.:|.|..|....  ..|:..|...|.:..:.
  Fly   353 FTSINHEEALKRCVQILKSSRQISMTVRAPPTLNS--TAPLHGFGPPSRDPMYASMAPPLHPQNQ 415

  Fly   370 -----------------------------------------FDQFPKARTVQVRKE--GFLGIMV 391
                                                     .::..:.|.|::..|  ..||:|:
  Fly   416 AAAAAAAAAASGAGLPFRQTCSWMDRHGRPASPPMEYGGRRSERRDRIRRVELLIEPGQSLGLMI 480

  Fly   392 IYGKHAEVGSGIFISDLREGSNAELAGVKVGDMLLAVNQDVTLESNYDDATGLLKRAEGVVTMIL 456
            ..|  .|.|.|||::.:.:.|.|:.:|:.:||.:|.||....|:..:|:|.|.||..:.:..:|
  Fly   481 RGG--VEYGLGIFVTGVDKDSVADRSGLMIGDEILEVNGQSFLDVTHDEAVGQLKYHKRMSLVI- 542

  Fly   457 LTLKSEEAIKAEKAAEEKKKEEAKKEEEKPQEPATAEIKP-----------NKKILIELKVEKKP 510
                                   :...:.|....:.|::|           .:|..|...||:|.
  Fly   543 -----------------------RDVGKVPHSCTSIEMEPWDAYSPTGTRARRKGQIATMVEEKA 584

  Fly   511 MGVIVCGGKNNHVTTGCVITHVYPEGQVAADKRLKIFDHICDINGTPIHVGSMTTLKVHQLFHTT 575
            ..::                   |....|:     :..:|.:.:...:.:.:...:.:..|  .|
  Fly   585 RSLL-------------------PRHHFAS-----LSYYIAEYSAKAMTIDAFVAVLLEML--DT 623

  Fly   576 YEKAVTLT-----VFRADPP---------ELEKFNVDLMKKAG---KELGLSLSPNEIGCTIADL 623
            |||...:|     ||..|..         |.:.::||..::.|   ::|.::....||   ||
  Fly   624 YEKHTLVTEIRELVFPEDRTRYDELVYRRERDPYSVDRHRRKGDPARDLPVTADDLEI---IA-- 683

  Fly   624 IQGQYPEIDSKL 635
            ..|:.|..||.|
  Fly   684 ATGRSPSSDSGL 695

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
inaD	NP_001246470.1	PDZ_signaling	27..115	CDD:238492
		PDZ_signaling	259..340	CDD:238492	18/83 (22%)
		PDZ_signaling	377..457	CDD:238492	27/81 (33%)
		PDZ_signaling	500..584	CDD:238492	13/88 (15%)
		PDZ_signaling	597..672	CDD:238492	13/42 (31%)
dysc	NP_001261810.1	PDZ_signaling	294..380	CDD:238492	19/86 (22%)
		PDZ_signaling	466..543	CDD:238492	26/102 (25%)
		HN_L-whirlin_R2_like	573..653	CDD:259823	17/105 (16%)
		PDZ_signaling	886..971	CDD:238492

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3528
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.900