DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment inaD and Zasp66

DIOPT Version :9

Sequence 1:	NP_001246470.1	Gene:	inaD / 37629	FlyBaseID:	FBgn0001263	Length:	686	Species:	Drosophila melanogaster
Sequence 2:	NP_729395.2	Gene:	Zasp66 / 38988	FlyBaseID:	FBgn0035917	Length:	430	Species:	Drosophila melanogaster

Alignment Length:	168	Identity:	33/168 - (19%)
Similarity:	53/168 - (31%)	Gaps:	56/168 - (33%)

- Green bases have known domain annotations that are detailed below.

  Fly    64 GIVPDSPAHLCGRLKVGDRILSLNGKDVRNSTEQAVIDLIKEADFKIELEIQ-----TFDKSDEQ 123
            |:...||||  |.|..||.|..:...|.|:.:......|.:.|..:|.|.:.     .:.:...|
  Fly    67 GVQVGSPAH--GELLRGDIISKIGEYDARDLSHADAQQLFRGAGNEIRLVVHRDNKIAYTQGATQ 129

  Fly   124 QAKSDPRSNG-----------------YMQAKNKFNQ---------EQTT--NNNASGGQGMGQG 160
            :|....|||.                 ::...:.|.:         .||.  ..|:|||
  Fly   130 EAGPGSRSNSTLPPVTPDLMPHRGPSPFLPGPSHFERALQLPVDTLPQTVFPQLNSSGG------ 188

  Fly   161 QGQGQGMAGMNRQQSMQKRNTTFTASMRQKHSNYADED 198
                           .:..:|.|:....:.|....||:
  Fly   189 ---------------YEVPSTVFSPKPTRDHQQDVDEE 211

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
inaD	NP_001246470.1	PDZ_signaling	27..115	CDD:238492	16/50 (32%)
		PDZ_signaling	259..340	CDD:238492
		PDZ_signaling	377..457	CDD:238492
		PDZ_signaling	500..584	CDD:238492
		PDZ_signaling	597..672	CDD:238492
Zasp66	NP_729395.2	PDZ_signaling	<68..115	CDD:238492	15/48 (31%)
Zasp66	NP_729395.2	DUF4749	285..359	CDD:292558
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3528
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.900