DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment inaD and Whrn

DIOPT Version :9

Sequence 1:	NP_001246470.1	Gene:	inaD / 37629	FlyBaseID:	FBgn0001263	Length:	686	Species:	Drosophila melanogaster
Sequence 2:	XP_038965801.1	Gene:	Whrn / 313255	RGDID:	631330	Length:	969	Species:	Rattus norvegicus

Alignment Length:	226	Identity:	58/226 - (25%)
Similarity:	100/226 - (44%)	Gaps:	30/226 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly   258 DLRRIEVQR-DASKPLGLALAGHKDRQKMACFVAGVDPNGALGSVDIKPGDEIVEVNGNVLKNRC 321
            ::|.:.::| .|.:.||.::.|..: ..:..:|:.|:|........::.||:|:.||...|....
  Rat   138 EVRLVSLRRAKAHEGLGFSIRGGSE-HGVGIYVSLVEPGSLAEKEGLRVGDQILRVNDKSLARVT 201

  Fly   322 HLNASAVFKNVDGDKLVM--ITSRRKP------------NDEGMCVKPIKKFPTASDETKFIFDQ 372
            |..|....|.  ..|||:  .::.|.|            :.:|....|....|..|...:...|:
  Rat   202 HAEAVKALKG--SKKLVLSVYSAGRIPGGYVTNHIYTWVDPQGRSTSPPSSLPHGSTLRQHEDDR 264

  Fly   373 FPKARTVQVRKEGFLGIMVIYGKH--------AEVGSGIFISDLREGSNAELAGVKVGDMLLAVN 429
            ......:|...|..:.:::..|:.        ||.|.||:|:.:..||.||.:|:||||.:|.||
  Rat   265 RSALHLLQSGDEKKVNLVLGDGRSLGLTIRGGAEYGLGIYITGVDPGSEAESSGLKVGDQILEVN 329

  Fly   430 QDVTLESNYDDATGLLKRAEGVVTMILLTLK 460
            ....|...:|:|..|||.:.    .::||:|
  Rat   330 GRSFLSILHDEAVKLLKSSR----HLILTVK 356

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
inaD	NP_001246470.1	PDZ_signaling	27..115	CDD:238492
		PDZ_signaling	259..340	CDD:238492	21/83 (25%)
		PDZ_signaling	377..457	CDD:238492	27/87 (31%)
		PDZ_signaling	500..584	CDD:238492
		PDZ_signaling	597..672	CDD:238492
Whrn	XP_038965801.1	HN_L-whirlin_R1_like	38..113	CDD:259822
		PDZ_signaling	139..216	CDD:238492	19/79 (24%)
		PDZ_signaling	276..356	CDD:238492	28/83 (34%)
		HN_L-whirlin_R2_like	418..498	CDD:259823
		PDZ_signaling	<908..949	CDD:238492
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3528
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900