Protein Alignment inaD and Pard3b

DIOPT Version :9

• Sequence 1: NP_001246470.1
• Gene: inaD / 37629
• FlyBaseID: FBgn0001263
• Length: 686
• Species: Drosophila melanogaster
• Sequence 2: NP_001178737.1
• Gene: Pard3b / 301455
• RGDID: 1584992
• Length: 1203
• Species: Rattus norvegicus
• Alignment Length: 613
• Identity: 119/613 - (19%)
• Similarity: 201/613 - (32%)
• Gaps: 214/613 - (34%)

  Fly   173 QQSMQKRNTTFTAS----MRQKHSNYAD--------------EDDE------DTRDMTGRIRTEA 213
            ||::|:...|....    ::..|..|.|              ||.:      |.::...:|.:.:
  Rat    28 QQALQRYLKTRDQDPGYWVKIHHLEYTDGGILDPDDVLADVVEDKDKLIAVFDEQEPLQKIESPS 92

  Fly   214 GYEIDRASAGNCKLNKQEKDRDKEQEDEFGYTMAKINKRYNMMKDLRRIEVQRDASKPLG----- 273
            |..:||.|                 .|.|...:|                .|..|.||:|
  Rat    93 GNPVDRQS-----------------PDAFDTEVA----------------AQLAAFKPIGGEIVV 124

  Fly   274 ------------------LALAGHKDRQKMACFVAGVDPNGALGSVDIKPGDEIVEVNGNVLKNR 320
                              .|...|.|.|.     :...|:|.    .:||   :|..:...|:||
  Rat   125 TPSALKLGTPLLVRRSSDPAPGPHADAQP-----STASPSGQ----SLKP---VVLDSAQNLENR 177

  Fly   321 CHLNASAVFKNVDGDKLVMITSRRKPNDEGMCVKPIKKFPTASDETKFIFDQFPKARTVQVRKEG 385
            ..:|         |::..::...:..|:             .||.|          |.|::..||
  Rat   178 DVMN---------GEQTGLLMLHKTKNE-------------LSDMT----------RAVEISGEG 210

  Fly   386 F-LGIMVIYGKHAEVGS--GIFISDLREGSNAELAGV-KVGDMLLAVNQDVTLESNYDDATGLLK 446
            . |||.|:....:..|.  |:||..:.|.|..:..|: :..:.::.:|....|:..:..|..:.:
  Rat   211 DPLGIHVVPFFSSLSGRILGLFIRGIEENSRCKQEGLFQENECIVKINNVELLDKTFAQAQDVFR 275

  Fly   447 RA---EGVVTMILLTLKSEE----------------------------------AIKAEKAAEEK 474
            :|   ..||..:||....|:                                  |:...:|...:
  Rat   276 QAMKSPSVVLHVLLPQNREQYEKSVIGQLNIFGNNDSASRTKAPPPTRGKAGLKAVNPTRANSPE 340

  Fly   475 KKEEAKKEE----------EKPQEPATAEI------KPNKKILIELKVEKKPMGV---IVCGGKN 520
            .:|....::          .||..|:.:.:      |..|||.|:||  |.|.|:   :|....:
  Rat   341 GEESPSPQQSKSPRVPRLGRKPSSPSLSPLMGFGSKKNAKKIKIDLK--KGPEGLGFTVVTRDSS 403

  Fly   521 NHVTTGCVITHVYPEGQVAADKRLKIFDHICDINGTPIHVGSMTTLKVHQLFHTTYEKAVTLTVF 585
            .|......:.::.|:|....|.||:..|.|.::||..: .|......|..|..|...:.|:|.:.
  Rat   404 IHGPGPIFVKNILPKGAAVKDGRLQSGDRILEVNGRDV-TGRTQEELVAMLRSTKQGETVSLVIA 467

  Fly   586 RAD----PPELE----------------KFNVDLMKKAGKELGLSLSPN-------EIGCTIADL 623
            |.:    |.||:                ...:.|.......||:||..|       ::|..|..:
  Rat   468 RQEGSFLPRELKGEPDCYALSLESSEQLTLEIPLNDSGSAGLGVSLKGNKSRETGTDLGIFIKSI 532

  Fly   624 IQGQYPEIDSKLQRGDIITKFNGDALEG 651
            |.|.....|.:|:..|.:...||:.|.|
  Rat   533 IHGGAAFKDGRLRMNDQLIAVNGETLLG 560

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
inaD	NP_001246470.1	PDZ_signaling	27..115	CDD:238492
		PDZ_signaling	259..340	CDD:238492	19/103 (18%)
		PDZ_signaling	377..457	CDD:238492	21/86 (24%)
		PDZ_signaling	500..584	CDD:238492	24/86 (28%)
		PDZ_signaling	597..672	CDD:238492	17/62 (27%)
Pard3b	NP_001178737.1	DUF3534	1..143	CDD:288873	23/147 (16%)
		PDZ_signaling	201..288	CDD:238492	22/96 (23%)
		PDZ	380..469	CDD:214570	26/91 (29%)
		PDZ_signaling	501..589	CDD:238492	17/60 (28%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3528
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900