DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment inaD and Pdzd7

DIOPT Version :9

Sequence 1:	NP_001246470.1	Gene:	inaD / 37629	FlyBaseID:	FBgn0001263	Length:	686	Species:	Drosophila melanogaster
Sequence 2:	NP_001099832.2	Gene:	Pdzd7 / 293996	RGDID:	1309882	Length:	1031	Species:	Rattus norvegicus

Alignment Length:	224	Identity:	59/224 - (26%)
Similarity:	96/224 - (42%)	Gaps:	32/224 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly   264 VQRDASKPLGLALAGHKDRQKMACFVAGVDPNGALGSVDIKPGDEIVEVNGNVLKNRCHLNASAV 328
            |::..|..||.::.|..: ..:..||:.|:...:.....:..||:|.||||..|::.  ...|||
  Rat    89 VEKSPSGRLGFSVRGGSE-HGLGIFVSKVEEGSSAERAGLCVGDKITEVNGLSLEST--TMGSAV 150

  Fly   329 FKNVDGDKLVMITSR--RKPNDEGMCVKPIKKFPTASD--ETKFIFDQFPKARTVQVRKEGFLGI 389
            .......:|.|:..|  |.|.     :|..|:..|..|  ..:.:.::.....:....::|...|
  Rat   151 RLLTSSSRLHMMVRRMGRVPG-----IKFSKEKTTWVDVVNRRLVVEKCSSTPSDSSSEDGVRRI 210

  Fly   390 MVIY--------------GKHAEVGSGIFISDLREGSNAELAGVKVGDMLLAVNQDVTLESNYDD 440
            :.:|              ||  |.|.||::|.:..|..||..|:||||.:||.|.....:.::..
  Rat   211 VHLYTTSDDFCLGFNIRGGK--EFGLGIYVSKVDHGGLAEENGIKVGDQVLAANGVRFDDISHSQ 273

  Fly   441 ATGLLKRAEGVVTMILLTLKSEEAIKAEK 469
            |..:||..    |.|:||:|......|.|
  Rat   274 AVEVLKGQ----THIMLTIKETGRYPAYK 298

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
inaD	NP_001246470.1	PDZ_signaling	27..115	CDD:238492
		PDZ_signaling	259..340	CDD:238492	20/75 (27%)
		PDZ_signaling	377..457	CDD:238492	26/93 (28%)
		PDZ_signaling	500..584	CDD:238492
		PDZ_signaling	597..672	CDD:238492
Pdzd7	NP_001099832.2	PDZ_signaling	84..164	CDD:238492	21/77 (27%)
		PDZ_signaling	209..289	CDD:238492	27/85 (32%)
		HN_PDZD7_like	555..632	CDD:259824
		PDZ_signaling	866..954	CDD:238492
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3528
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900