DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment inaD and F28E10.4

DIOPT Version :9

Sequence 1:	NP_001246470.1	Gene:	inaD / 37629	FlyBaseID:	FBgn0001263	Length:	686	Species:	Drosophila melanogaster
Sequence 2:	NP_500590.2	Gene:	F28E10.4 / 185067	WormBaseID:	WBGene00017902	Length:	324	Species:	Caenorhabditis elegans

Alignment Length:	264	Identity:	58/264 - (21%)
Similarity:	104/264 - (39%)	Gaps:	69/264 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly   216 EIDRASAGNCKLNKQEKDRDKEQEDEFGYTMAKINKRYNMMKDLRR------IEVQRD---ASKP 271
            |:.|.:|.|.::::::           |.|.....:......:||:      ::|:|.   .:..
Worm    80 ELLRGTACNVEVSRRK-----------GVTPVTCERLAKSGCNLRKGHACFVLDVERPPHMTTTS 133

  Fly   272 LGLALAGHKDRQKMACFVAGVDPNGALGSVDIKPGDEIVEVNG----------NVLKNRCHLNAS 326
            :||.|...|.|    .||..|||| .:.|.....||.|::::|          |.::.  ||:..
Worm   134 VGLKLGIIKRR----AFVTKVDPN-TIASSFFGCGDSIMDMSGAPIPMTDNPDNFIRE--HLSRL 191

  Fly   327 AVFKNVDGDKLVMITSRRKPNDEGMCVKPIKKF--PTASDETKFIFDQFPKARTVQVRKEGFLGI 389
            :.     |.|:..:..|  |....| .|..:||  ....|:::....|    ..:::.:|.....
Worm   192 ST-----GAKVSFLVER--PISVAM-AKQYQKFIESITYDDSEVEMAQ----DVIEIGREASNMH 244

  Fly   390 MVIYGKHAEVGSGIFISDL--REGSNAELAGVKVGDMLLA-------VNQDVTLESNYDDATGLL 445
            .:|..|  .|...|..||:  |:.||.:.:....|.:.::       :..|||   ::||    |
Worm   245 FMILKK--LVTPSILSSDVRRRKKSNNKTSESTEGSITISSASTEMKITSDVT---DFDD----L 300

  Fly   446 KRAE 449
            |..|
Worm   301 KPVE 304

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
inaD	NP_001246470.1	PDZ_signaling	27..115	CDD:238492
		PDZ_signaling	259..340	CDD:238492	25/99 (25%)
		PDZ_signaling	377..457	CDD:238492	19/82 (23%)
		PDZ_signaling	500..584	CDD:238492
		PDZ_signaling	597..672	CDD:238492
F28E10.4	NP_500590.2	None
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3528
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900