DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment inaD and C46H11.6

DIOPT Version :9

Sequence 1:	NP_001246470.1	Gene:	inaD / 37629	FlyBaseID:	FBgn0001263	Length:	686	Species:	Drosophila melanogaster
Sequence 2:	NP_491502.1	Gene:	C46H11.6 / 183523	WormBaseID:	WBGene00016730	Length:	342	Species:	Caenorhabditis elegans

Alignment Length:	287	Identity:	60/287 - (20%)
Similarity:	104/287 - (36%)	Gaps:	74/287 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly   265 QRDASKPLGLALAGHKDRQKMACFVA-GVDPNGALGSVDIKPGDEIVEVN---GNVLKNRCHL-N 324
            ::|..||....:  ..:...|..|:: ....||.:.|      |:||:||   ||:.|.:..| .
Worm    38 EKDVGKPANEVI--RINENSMVSFLSTNSFYNGLILS------DKIVKVNGASGNISKYQTELMK 94

  Fly   325 ASAVFKNVDGDKLVMITSRRKPNDEGMCVKPIKKFPTASDETKFIFDQFPKARTVQVRKEGFLGI 389
            .......|...|.::..:|.:....| ||       ...|.|.|:.:    .......|...:|:
Worm    95 GETCSVEVTRRKNIIPATRERLKKSG-CV-------LRRDNTCFVIE----VEKTSAMKSATVGV 147

  Fly   390 MVIYGKHAEV--------------GSGIFISDLREGS--NAE---------LAGVKVGD-MLLAV 428
            .|.|.:...:              |.|..|.|:.|.|  |||         |:|:..|: :...|
Worm   148 TVTYIQKRGIVTRIEPSSLASIFFGRGDLIMDINEESILNAEKNDDFIREKLSGILKGEKVTFLV 212

  Fly   429 NQDVTLES------------------NYDDATGLLKRAEGVVTMILLTLK-----SEEAIKAEKA 470
            .:.|::||                  ..:||..:.:.|..:...:|..|:     |.:..|.:..
Worm   213 ERPVSVESANTLRHLIESVAPDPDVKMANDAICIGRNASNMHYNVLKKLQPKSILSRDVFKGKNP 277

  Fly   471 AEEKKKEEAKKEEEKPQEPATAEIKPN 497
            .|:|..::..||::...:.:||....|
Worm   278 REKKPGKKLSKEKDNTIKISTATSTAN 304

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
inaD	NP_001246470.1	PDZ_signaling	27..115	CDD:238492
		PDZ_signaling	259..340	CDD:238492	19/79 (24%)
		PDZ_signaling	377..457	CDD:238492	23/123 (19%)
		PDZ_signaling	500..584	CDD:238492
		PDZ_signaling	597..672	CDD:238492
C46H11.6	NP_491502.1	None
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3528
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900