Protein Alignment inaD and Il16

DIOPT Version :9

• Sequence 1: NP_001246470.1
• Gene: inaD / 37629
• FlyBaseID: FBgn0001263
• Length: 686
• Species: Drosophila melanogaster
• Sequence 2: NP_001347016.1
• Gene: Il16 / 16170
• MGIID: 1270855
• Length: 1424
• Species: Mus musculus
• Alignment Length: 569
• Identity: 113/569 - (19%)
• Similarity: 209/569 - (36%)
• Gaps: 129/569 - (22%)

  Fly   173 QQSMQKRNTTFTASMRQKHSNYADEDDEDTRDMTGRIRTEAGYEIDRA-SAGNCKLNKQEKDRDK 236
            :|..:||.  .|:|:|.:...::.:..:.|:..:          |.|: ...|.|.:......|:
Mouse    89 EQERKKRG--LTSSLRMEPHGHSGKSRKSTKFRS----------ISRSLILCNAKTSDDGSSPDE 141

  Fly   237 EQEDEF---------GYTMAKINKRYNMMKDLRRIEVQRDASKPLGLALAGHKDRQKMACFVAGV 292
            :..|.|         |:..:.:.........|..|.....||....||.|| .||.|....:..:
Mouse   142 KYPDPFETSLCQGKEGFFHSSMQLADTFEAGLSNIPDLALASDSAQLAAAG-SDRGKHCRKMFFM 205

  Fly   293 DPNGALGSVDIKPGDEIVEVNGNVLKNRCH----LNASAVFKNVDGD-KLVMITSRRKPNDE--- 349
            ..:.:..|.: |.|....:.:..:....||    .|:::|.....|: ...|......|.|.
Mouse   206 KESSSTSSKE-KSGKPEAQSSSFLFPKACHQRTRSNSTSVNPYSAGEIDFPMTKKSAAPTDRQPY 269

  Fly   350 GMC-----------------VKPIKKFPTASDETKFIFDQFPKARTVQV---------RKEGFLG 388
            .:|                 .:|.:...||.      ..|........|         :.:| ||
Mouse   270 SLCSNRKSLSQQLDYPILGTARPTRSLSTAQ------LGQLSGGLQASVISNIVLMKGQAKG-LG 327

  Fly   389 IMVIYGKHAEVGS-GIFISDLREGSNAELAG-VKVGDMLLAVNQDVTLESNYDDATGLLKRA-EG 450
            ..::.||.:..|. ||::..:..|..|...| ::.||.:|.:|.:......:.||....|:| :|
Mouse   328 FSIVGGKDSIYGPIGIYVKSIFAGGAAAADGRLQEGDEILELNGESMAGLTHQDALQKFKQAKKG 392

  Fly   451 VVTMILLTL----------KSEEAIKAEKAAEEKKKEEAKKEEEKPQEPATAEIKPNKKILIELK 505
            ::|:.:.|.          .|....::..::....::.:....|.|..||:. .|||.:|::|:.
Mouse   393 LLTLTVRTRLTTPPSLCSHLSPPLCRSLSSSTCGAQDSSPFSLESPASPAST-AKPNYRIMVEVS 456

  Fly   506 VEKKP---MGVIVCGGKNNHVTTGCVITHVYPEGQVA-ADKRLKIFDHICDINGTPIHVGSMTTL 566
            ::|:.   :|:.:|........:| :..|....|.|| .|.||:..|.|.:||.:|:|  .:|..
Mouse   457 LKKEAGVGLGIGLCSIPYFQCISG-IFVHTLSPGSVAHLDGRLRCGDEIVEINDSPVH--CLTLN 518

  Fly   567 KVHQLFHTTYEKAVTLTVFRADPPELEKFNVDLMKKAGKELGLSLSPNEIGCTIADLIQGQYPEI 631
            :|:.:........|.:.|.|...|::.:   ..:|:|                :|..::|
Mouse   519 EVYTILSHCDPGPVPIIVSRHPDPQVSE---QQLKEA----------------VAQAVEG----- 559

  Fly   632 DSKLQRGDIITKFNGD----ALEGLPFQVCYALFKGANGKVSMEVTRPK 676
                      .||..|    :|||:.     .|....:|:.::|..|.|
Mouse   560 ----------VKFGKDRHQWSLEGVK-----RLESSWHGRPTLEKEREK 593

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
inaD	NP_001246470.1	PDZ_signaling	27..115	CDD:238492
		PDZ_signaling	259..340	CDD:238492	19/85 (22%)
		PDZ_signaling	377..457	CDD:238492	22/91 (24%)
		PDZ_signaling	500..584	CDD:238492	22/87 (25%)
		PDZ_signaling	597..672	CDD:238492	12/78 (15%)
Il16	NP_001347016.1	PDZ_signaling	316..391	CDD:238492	19/75 (25%)
		PDZ_signaling	454..536	CDD:238492	21/84 (25%)
		Atrophin-1	<620..931	CDD:331285
		PDZ_signaling	1206..1283	CDD:238492
		PDZ_signaling	1328..1409	CDD:238492

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3528
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900