Protein Alignment inaD and Patj

DIOPT Version :10

• Sequence 1: NP_001246470.1
• Gene: inaD / 37629
• FlyBaseID: FBgn0001263
• Length: 686
• Species: Drosophila melanogaster
• Sequence 2: NP_766284.2
• Gene: Patj / 12695
• MGIID: 1277960
• Length: 1834
• Species: Mus musculus
• Alignment Length: 689
• Identity: 182/689 - (26%)
• Similarity: 283/689 - (41%)
• Gaps: 142/689 - (20%)

  Fly    24 PELIH-----MVTLDKTGKKSFGICIVRGE-----VKDSPNTKTTGIFIKGIVPDSPAHLCGRLK 78
            |...|     :|.:.:....|.||.||.|:     :|:....|  |||||.::.||||.....||
Mouse  1064 PNFSHWGPPRIVEIFREPNVSLGISIVGGQTVIKRLKNGEELK--GIFIKQVLEDSPAGKTNALK 1126

  Fly    79 VGDRILSLNGKDVRNSTEQAVIDLIKEADFKIELEIQTFDKSDEQQAKSDPRSNGYMQAKNKF-- 141
            .||:||.::|.|::|::....::.||.|...:...:|:.        .|.||....:..|.|.
Mouse  1127 TGDKILEVSGVDLQNASHAEAVEAIKSAGNPVVFVVQSL--------SSTPRVIPTVNNKGKTPA 1183

  Fly   142 -NQEQTTNNNASGGQGMGQGQGQGQGMAGMNRQQSMQKRNTTFTASMRQKHSNYADEDDEDTRDM 205
             ||:|                         |.|:...||:.|....|:......|     .:.||
Mouse  1184 PNQDQ-------------------------NTQERKAKRHGTAPPPMKLPPPYRA-----PSADM 1218

  Fly   206 TGRIRTEAGYEIDRASAGNCKLNKQEKDRDKEQEDEFGYTMAKINKRY-NMMKDLRRIEVQRDAS 269
            .|                              .|::...|..||.:|| ::..:|..||:::| .
Mouse  1219 EG------------------------------SEEDCALTDKKIRQRYADLPGELHIIELEKD-K 1252

  Fly   270 KPLGLALAGHKDRQKMACFVAGVDPNG-ALGSVDIKPGDEIVEVNGNVLKNRCHLNASAVFKNVD 333
            ..|||:|||:|||.:|:.||.|::|.| |.....::.|||::|:|..:|..|.|.||||:.|...
Mouse  1253 NGLGLSLAGNKDRSRMSIFVVGINPEGPAAADGRMRIGDELLEINNQILYGRSHQNASAIIKTAP 1317

  Fly   334 GD-KLVMITSRRKPNDEGMCVKPIKKFPTASDETKFIFDQFPKARTVQVRKEGFLGIMVIYGKHA 397
            .. |||.|.     |::.:....:..||..|.....:.|               ||...:.....
Mouse  1318 TRVKLVFIR-----NEDAVSQMAVAPFPELSHSPSPVED---------------LGGTELVSSEE 1362

  Fly   398 EVGSGIFISDL--REGSNAELAGVKVGDMLLAVNQDVTLESNYDDATGLLKRAEGVVTMILLTLK 460
            |  |.:....|  .|.|..|.....|.|.::|..|.   ||...|:.....:.:...|.:..:.:
Mouse  1363 E--SSVDAKHLPEPESSKPEDLSQVVDDNMVAEQQK---ESESPDSAACQIKQQTYSTQVSSSSQ 1422

  Fly   461 SEEAIKAEKAAEEKKKEEAKKEEEKP---------QEPATAEIKPNKKILIELKVEKKPMGVIVC 516
            ...:..|................:.|         .:|||..|.|.::::||:...:..:|:.:.
Mouse  1423 DSPSSPAPLCQSAHADVTGSGNFQAPLPVDPAPLSVDPATCPIVPGQEMIIEISKGRSGLGLSIV 1487

  Fly   517 GGKNNHVTTGCVITHVYPEGQVAADKRLKIFDHICDINGTPI----HVGSMTTLKVHQLFHTTYE 577
            |||:..: ...||..||.||..|.|.||...|.|.::||..:    |..::|.|:      .|.:
Mouse  1488 GGKDTPL-DAIVIHEVYEEGAAARDGRLWAGDQILEVNGVDLRSSSHEEAITALR------QTPQ 1545

  Fly   578 KAVTLTVFR-----ADPPELEKFNVDLMKKAGKELGLSL--SPNEIGCTIADLIQGQYPEIDSKL 635
            | |.|.|:|     .|...||.|.|||.||.|:.||||:  ..:..|..|:|:::|...::|.:|
Mouse  1546 K-VRLVVYRDEAQYRDEENLEVFLVDLQKKTGRGLGLSIVGKRSGSGVFISDIVKGGAADLDGRL 1609

  Fly   636 QRGDIITKFNGDALEGLPFQVCYALFKGANGKVSMEVTR 674
            .|||.|...||:.:.....:....:.|...|.|.:|:.|
Mouse  1610 IRGDQILSVNGEDMRHASQETVATILKCVQGLVQLEIGR 1648

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
inaD	NP_001246470.1	PDZ1_INAD-like	29..115	CDD:467276	30/90 (33%)
		PDZ8_MUPP1-PDZ7_PATJ-PDZ2_INAD-like	259..342	CDD:467160	37/84 (44%)
		PDZ3_INAD-like	379..454	CDD:467277	15/76 (20%)
		PDZ4_INAD-like	501..585	CDD:467278	27/87 (31%)
		PDZ5_INAD-like	596..674	CDD:467279	26/79 (33%)
Patj	NP_766284.2	L27_2	8..65	CDD:312549
		PDZ1_MUPP1-like	118..219	CDD:467176
		PDZ2_MUPP1-like	247..326	CDD:467155
		PDZ3_MUPP1-like	362..451	CDD:467253
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	456..488
		PDZ4_MUPP1-like	555..639	CDD:467156
		PDZ5_MUPP1-like	679..775	CDD:467157
		PDZ7_MUPP1-PD6_PATJ-like	1071..1166	CDD:467159	31/104 (30%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1171..1219		13/77 (17%)
		PDZ8_MUPP1-PDZ7_PATJ-PDZ2_INAD-like	1243..1326	CDD:467160	36/83 (43%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1340..1453		21/132 (16%)
		MPDZ_u10	<1453..1468	CDD:435500	4/14 (29%)
		PDZ10_MUPP1-PDZ8_PATJ-like	1468..1553	CDD:467161	28/92 (30%)
		PDZ11_MUPP1-PDZ9_PATJ-like	1564..1650	CDD:467162	30/85 (35%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1657..1676
		PDZ12_MUPP1-like	1708..1793	CDD:467163
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1811..1834