Protein Alignment inaD and inaD

DIOPT Version :10

• Sequence 1: NP_001246470.1
• Gene: inaD / 37629
• FlyBaseID: FBgn0001263
• Length: 686
• Species: Drosophila melanogaster
• Sequence 2: XP_061501956.1
• Gene: inaD / 1269413
• VectorBaseID: AGAMI1_001959
• Length: 780
• Species: Anopheles gambiae
• Alignment Length: 678
• Identity: 264/678 - (38%)
• Similarity: 393/678 - (57%)
• Gaps: 54/678 - (7%)

  Fly    30 VTLDKTGKKSFGICIVRGEVKDSPNTKTTGIFIKGIVPDSPAHLCGRLKVGDRILSLNGKDVRNS 94
            |.::||.|.|||..||.|:|....:. |:|:|||.|:|:|||..||.||:|||||::|...:.|:
Mosquito   120 VVIEKTEKSSFGFSIVGGKVNVGGDV-TSGLFIKSIIPESPADKCGELKIGDRILAVNENSLENA 183

  Fly    95 TEQAVIDLIKEADFKIELEIQTFDKSDEQQAKSDPRSNGYMQAKNKFNQEQTTNNNASGGQGMGQ 159
            :.:..::.||.|:.:|.|.:|:.:::..:|  ::|     |..:.|. ....|.:.....:.:..
Mosquito   184 SHEKAVNYIKTANDRIVLVVQSLERTVREQ--TNP-----MVLQKKV-PPPVTPSKTPEVEYIQD 240

  Fly   160 GQGQGQGMAGM--NRQQSMQKRNTTFTASMRQKHSNYADEDDEDTRDMTGRIRTEAGYEIDRASA 222
            |:.:.|.:|..  |:..|:.|      |......|..:.:|:||:|:|.|:..|:||.|||||||
Mosquito   241 GKPKKQPVATPEDNKTLSVPK------ARQESTDSENSSDDEEDSREMEGKTFTKAGVEIDRASA 299

  Fly   223 GNCKLNKQEKDRDKEQEDEFGYTMAKINKRYNMMKDLRRIEVQRDASKPLGLALAGHKDRQKMAC 287
            ||.|:.::    |.|:||::||||.||.|||..:.::....:.||:::..||:|.||:||.:|||
Mosquito   300 GNTKIGEE----DAEEEDDYGYTMKKIKKRYAGLGEVDVCTILRDSNETCGLSLCGHRDRTRMAC 360

  Fly   288 FVAGVDPNGALGSVDIKPGDEIVEVNGNVLKNRCHLNASAVFKNVDGDKLVMITSRRKPNDEGMC 352
            .:||::|.||.....:..|||::||||.||..|||||.|.:.||:....|..|..|:|.:.:.|.
Mosquito   361 LIAGINPKGAAAGTSLTVGDEVLEVNGTVLHGRCHLNCSVMIKNLASPTLKFIVLRKKTSPDDMA 425

  Fly   353 VKPIKKFPTASDETKFIFDQFPKARTVQVRK-EGFLGIMVIYGKHAEVGSGIFISDLREGSNAEL 416
            |||:|.|||..|.|..|.::|...:|:.|:| ...||||:|.|||:..|.||||||::|||.||.
Mosquito   426 VKPVKHFPTDIDYTDNIMEKFKDVKTITVKKGTSSLGIMIIEGKHSIAGQGIFISDIQEGSTAEK 490

  Fly   417 AGVKVGDMLLAVNQDVTLESNYDDATGLLKRAEGVVTMILLTLKSEEAIKAEKAA---------- 471
            :|:|:||||||||:|..|..||:.|.||||:||||:|:.:.....|:  :::|.|
Mosquito   491 SGLKIGDMLLAVNRDSLLGCNYETAAGLLKKAEGVITLKICNPNKEK--ESDKPANGTAVPGTTP 553

  Fly   472 EEKKKEE-------------AKKEEEKPQ----EPATAEIKPNKKILIELKVEKKPMGVIVCGGK 519
            .:||.||             ..|.|..|.    :|..|.|..|...:|::..|.||:|:||.||.
Mosquito   554 SKKKTEEMATLATSRAGTPHGTKPEPSPTKEVIDPLKAPINDNDFTVIDIPTEGKPLGIIVAGGC 618

  Fly   520 NNHVTTGCVITHVYPEGQVAADKRLKIFDHICDINGTPIHVGSMTTLKVHQLFHTTYEKAVTLTV 584
            ::.|.:|..:..:.|:..|..|.||:|||.|.:|||..:: .:.|:..:.:.....:.| |.|.|
Mosquito   619 DSLVKSGAAVMDILPQSVVEKDNRLQIFDQIVEINGFKVN-NTCTSEAIKRAVKQLHPK-VRLIV 681

  Fly   585 FRADPPELEKFNVDLMKKAGKELGLSL-SPNEIGCTIADLIQGQYPEIDSKLQRGDIITKFNGDA 648
            :||:||..|...||||||.||.|||:. :.|..|..|..|:.|...|.|.::|.|||::..|||:
Mosquito   682 YRANPPTTETVEVDLMKKPGKNLGLTFRAGNPKGIVITSLVPGGSAEFDGRIQLGDIVSHINGDS 746

  Fly   649 LEGLPFQVCYALFKGANGKVSMEVTRPK 676
            ||....:.|.:|.|.|.|||.:.:.|||
Mosquito   747 LEAGGIEQCASLLKTAQGKVGLRILRPK 774

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
inaD	NP_001246470.1	PDZ1_INAD-like	29..115	CDD:467276	37/84 (44%)
		PDZ8_MUPP1-PDZ7_PATJ-PDZ2_INAD-like	259..342	CDD:467160	36/82 (44%)
		PDZ3_INAD-like	379..454	CDD:467277	45/75 (60%)
		PDZ4_INAD-like	501..585	CDD:467278	27/83 (33%)
		PDZ5_INAD-like	596..674	CDD:467279	34/78 (44%)
inaD	XP_061501956.1	None