DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment inaD and Slc9a3r2

DIOPT Version :9

Sequence 1:NP_001246470.1 Gene:inaD / 37629 FlyBaseID:FBgn0001263 Length:686 Species:Drosophila melanogaster
Sequence 2:NP_446263.2 Gene:Slc9a3r2 / 116501 RGDID:620380 Length:337 Species:Rattus norvegicus


Alignment Length:411 Identity:77/411 - (18%)
Similarity:126/411 - (30%) Gaps:156/411 - (37%)


- Green bases have known domain annotations that are detailed below.


  Fly    24 PELIHMVTLDKTGKKSFGICIVRGEVKDSPNTKTTGIFIKGIVPDSPAHLCGRLKVGDRILSLNG 88
            |.|..:|    .|::.:|..: .||      ....|.||:.:.|.|||. ...|:.|||::.:||
  Rat     9 PRLCRLV----RGEQGYGFHL-HGE------KGRRGQFIRRVEPGSPAE-AAALRAGDRLVEVNG 61

  Fly    89 KDVRNSTEQAVIDLIKEADFKIELEIQTFDK-SDEQQAK------SDPRSNGYMQAKNKFNQEQT 146
            .:|...|...|:..||..:.:.:|.:  .|| :||:..:      .:....|...|.|.:  |..
  Rat    62 VNVEGETHHQVVQRIKAVEGQTQLLV--VDKETDEELCRRQLTCTEEMAHRGLPPAHNPW--EPK 122

  Fly   147 TNNNASGGQGMGQGQGQGQGMAGMNRQQSMQKRNTTFTASMRQKHSNYADEDDEDTRDMTGRIRT 211
            .:...||..|...||....|                                  ..|::..|:  
  Rat   123 PDWACSGSLGSDTGQKDVNG----------------------------------PPRELRPRL-- 151

  Fly   212 EAGYEIDRASAGNCKLNKQEKDRDKEQEDEFGYTMAKINKRYNMMKDLRRIEVQRDASKPLGLAL 276
                         |.|.:                                        .|.|...
  Rat   152 -------------CHLRR----------------------------------------GPQGYGF 163

  Fly   277 AGHKDRQKMACFVAGVDPNGALGSVDIKPGDEIVEVNGNVLKNRCHLNASAVFKNVDGDKLVMIT 341
            ..|.|:.:...::..|||........::..|.::||||               :||:|.:...:.
  Rat   164 NLHSDKSRPGQYIRSVDPGSPASLSGLRAQDRLIEVNG---------------QNVEGLRHAEVV 213

  Fly   342 SRRKPNDEGMCVKPIKKFPTASDETKFIF------DQFPKARTVQVRK--EGFLGIMVIYGKH-A 397
            :|.|..:               ||.:.:.      :.|.:.|.|....  ||.|...|..|.. |
  Rat   214 ARIKAQE---------------DEARLLVVDPETDEHFKRLRVVPTEDHVEGPLPSPVTNGTSLA 263

  Fly   398 EVGSGIFISDLREGSNAELAG 418
            ::..|...|     |.::|.|
  Rat   264 QLNGGSVCS-----SRSDLPG 279

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
inaDNP_001246470.1 PDZ_signaling 27..115 CDD:238492 24/87 (28%)
PDZ_signaling 259..340 CDD:238492 15/80 (19%)
PDZ_signaling 377..457 CDD:238492 13/45 (29%)
PDZ_signaling 500..584 CDD:238492
PDZ_signaling 597..672 CDD:238492
Slc9a3r2NP_446263.2 PDZ_signaling 9..88 CDD:238492 26/92 (28%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 127..146 6/52 (12%)
PDZ_signaling 149..228 CDD:238492 22/163 (13%)
EBP50_C 232..337 CDD:401087 14/53 (26%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 246..337 11/39 (28%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG3528
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.900

Return to query results.
Submit another query.