DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment inaD and SYNJ2BP-COX16

DIOPT Version :9

Sequence 1:	NP_001246470.1	Gene:	inaD / 37629	FlyBaseID:	FBgn0001263	Length:	686	Species:	Drosophila melanogaster
Sequence 2:	NP_001189476.1	Gene:	SYNJ2BP-COX16 / 100529257	HGNCID:	48350	Length:	191	Species:	Homo sapiens

Alignment Length:	92	Identity:	30/92 - (32%)
Similarity:	50/92 - (54%)	Gaps:	5/92 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly    28 HMVTLDK----TGKKSFGICIVRGEVKDSPNTKTTGIFIKGIVPDSPAHLCGRLKVGDRILSLNG 88
            ::||.::    .|....|..|| |.......:..:||::..|..:..|.|.|||:.||:|||:||
Human     7 YLVTEEEINLTRGPSGLGFNIV-GGTDQQYVSNDSGIYVSRIKENGAAALDGRLQEGDKILSVNG 70

  Fly    89 KDVRNSTEQAVIDLIKEADFKIELEIQ 115
            :|::|...|..:||.:.|.:.:.|.:|
Human    71 QDLKNLLHQDAVDLFRNAGYAVSLRVQ 97

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
inaD	NP_001246470.1	PDZ_signaling	27..115	CDD:238492	29/90 (32%)
		PDZ_signaling	259..340	CDD:238492
		PDZ_signaling	377..457	CDD:238492
		PDZ_signaling	500..584	CDD:238492
		PDZ_signaling	597..672	CDD:238492
SYNJ2BP-COX16	NP_001189476.1	PDZ_signaling	13..97	CDD:238492	27/84 (32%)
		DegQ	<16..77	CDD:223343	22/61 (36%)
		COX16	<133..173	CDD:290843
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3528
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.900