|
Fly 49 KIPVSEYRHYFYDVVQAYVQRL--------------LSERLVCKAEDVIRNVDRDVK------CF 93
:||.:: .|:.:.....||| |.:..|.:|..::||:...|: ||
Mouse 693 RIPEAQ---TFFRISGHSAQRLEELVRIGLDLAFDSLKKNNVEEASRLLRNMGFSVEDELLKICF 754
Fly 94 FFQFACECQDEELSEFVLDHLRSREPLMYEQEEPVLAYHWSLVQQLRECEALVAKH-----RTQ- 152
: ..|:.:.:|:::.|:.:|....::...| ..|.|| |||.:.| :||
Mouse 755 Y------TTDKNIRDFLVEILKEKECFSEKERRTV-----DFVHQL---EALYSGHFQENAQTQA 805
Fly 153 LPRVHIEAMMTLPEQA--------------------------------------LQLLLVELYFA 179
.||..|:.......:: |:.|..|.|.|
Mouse 806 FPRYWIKEQDCFKHKSVLDTFLKYDKKDEFHKQDHRIALNWAHRWDLQTQECILLRRLSPEEYKA 870
Fly 180 NGNESLLGSLSKDMVWQHLVDSDEQAKLQRWCRLQEEGFVSQETLSPLEQSFTAWKIDATMYEYA 244
...|:| |:||....:.:.:..|. |.|.:|||.||.:..:.....| .
Mouse 871 RSPEAL---------WRHLTARHDCSSISLWM----EEFQTQETESPQQSKWPPLSAD------I 916
Fly 245 VEE-----LQQPSEVLRNFFARAGYFFMDESEDIPSLLRRLCTMECLGKHADLLSRQPLAK---- 300
:|: ....:|:| :..||:|.|...|.||...||.||..:. |...|.|..|....
Mouse 917 IEQGTCCHSHMRNEIL-DKLARSGIFLASELEDFERLLLRLSRIG--GVMQDSLPVQSYKSRAGC 978
Fly 301 --------YLLDRGQYSLL-----LMECVPIASLELLAGTETHQ-EPLINLIVDIK--TNSLTEN 349
|.|:.|...|| ..:..| .:...|...|.|: .|.:..:|..: :::||:.
Mouse 979 DFHSRFILYCLEHGLQHLLYTYLDYYKLSP-GNCPFLEKKELHEAHPWLEFLVQCRQVSSNLTDP 1042
Fly 350 E-GFELISKSVQAYLEKTHDTVDS--FEGHPLL----TFYDFLG---------QEPSVRSLEGFL 398
: .|:....:.|..:.....:|.| .|||.|| |.|...| .|..::.::..|
Mouse 1043 KLIFQASLANAQILIPTNQASVSSMLLEGHTLLALATTMYAPGGVSQVIQNEDSENCLKKVDPQL 1107
Fly 399 TSTNLGRVPYLKSLIARFDHGPTSCNFGLPTAH-----------DLFMKFKHVNLPLLATAGHGE 452
....|...|.||:.:......|:.....:...| .||: ::..|...:...| .:
Mouse 1108 LKVALTPYPKLKAALFPQYTAPSILPSDITLYHLIQSLPPFDPSRLFV-WQSANTLAIGDTG-SQ 1170
Fly 453 LVCFSNARLSQRYARKSQLNYTHYLKQQRSAYAVYYLITEQL-------QLYGQITKTQLFHACE 510
|..||:..|..:||...:|||.:||...|.::|....:.::| ||..|:.| |
Mouse 1171 LPHFSSPDLVSKYAVLERLNYAYYLHHGRPSFAFGTFLVQELIKSKTPKQLIQQVGK-------E 1228
Fly 511 TVTQIALQHAGDDELVTHCVACCEMLGFDTQPLR---------------------SFL--LLQRK 552
..| :.|....:..:...||...|:||..:..|| ||: .|..|
Mouse 1229 AYT-LGLSSFTNPSVGAACVCFLELLGLSSLKLRVDLKMANVILGSKRRDEDARSSFIRESLAEK 1292
Fly 553 LPKCETGQ--SYSELL-----GEWD----RDLVEMLEANPSEFPLELYQSLMRLAIRDTPGKLPM 606
|.|...|. :..||| |.|| :....:...:.|::.|.|...::. ..||.:
Mouse 1293 LSKLADGDRAATEELLVLLEEGVWDSIEQQGFSRLSSESSSQWALVLQFCMLH------DRKLSV 1351
Fly 607 DLLKRYASKNNWWHLLLVFQFFDLPLSELKKLLPHFKSSPIGVHLLRALSYESSGDRHHKRTLQR 671
..|:..|..|:|...|:..|..:...:|::.||.:| ||: ||.
Mouse 1352 SYLRECAKANDWLQFLVHSQLHNYHPAEVESLLQYF--SPV---------------------LQS 1393
Fly 672 PTRRSGETQTNSSQETMTNSSHSSNQDSSVQQLQRNTDQSLCTLLTHTARQDVFAIILCSTNSLP 736
..:.:.|..::.| .|..||.:|:||:|..:
Mouse 1394 HLKLASEKLSSGS---------ISRDDSCLQELQKNKGE-------------------------- 1423
Fly 737 DELIATTPKFLEMMVGNSSHCSSIN-LLRHCIRQELPILAVLAATISEQNRDWCWIVW------- 793
|..|.|::...|...:|.: ||...:|...|||:|||:.:...:...|..||
Mouse 1424 ------TSNFFEILHRCSDESTSWSWLLAEAVRHRAPILSVLASCVQGASVVSCLCVWIVTSVED 1482
Fly 794 -----------LSVASGQWSLQLQEASKVRDENRSEWVWSVIRGAVAGGHLNALLHSLEIFHPDC 847
:||....|||: ....:| |..:.....:.|:...::|..|.
Mouse 1483 KVAAEAMGHIQISVEDHHWSLK-----------DLSIIW---RTVLTRRKSHTLIRGFQLFIKDS 1533
Fly 848 KLT------HLCRF--------LQLTGHQEDFSDATIVELRQFFF---SWSQDSVALPLCGPLPR 895
.|. .||.| ::|...|:.......|..|.... ||.:|.|.. |...:|:
Mouse 1534 PLLLIMEMYELCMFFKNYEKAKVKLLEFQKSLETLDTVAARVLPIIPASWMKDQVCF-LLKLMPQ 1597
Fly 896 KQLMQRSIGLLLIQLQSNFDCILQQQRFLECICRSDVGDICDLLDFCLLHKVF---GVAATWLRE 957
:...|..:|.|| || .:..:|.| ||..|:..| |||.:|. .:|.:....
Mouse 1598 QCETQYELGKLL-QL-----FVGTEQLF------SDGPDVQKL---CLLSQVLKDTPIAISPAVI 1647
Fly 958 LSIDLEQLGRRDSPEYKRLVDALTEARAYEEALQLATLLQLPLTDIVYGKWMTELEAGQLRP--- 1019
.|...|...| |.:.:::.|.....:..|.::|.|..||:..::..:...|::.....|
Mouse 1648 SSYSTENFQR----ECRSILEKLKADGQFAVARRVAELAALPVDSLLIEQLTQEMQTLTHTPQWS 1708
Fly 1020 ------------HEEYEKDIQQHALAPAILVNFLLQAASV----VGQVSLRRYELLQSTLGVIKK 1068
||.::|:......|.:. |..||..| ..|.||....||.:..|
Mouse 1709 LKQERLGFWKKCHEIFKKNSISKRAASSF---FSSQAPEVSEHPAEQGSLEERHLLLTLAG---- 1766
Fly 1069 HHLFPNESF---DRDQIEYDMVLCYLQ------LPEEQLPQLS---IYHSEYFEQIMLQERCVLY 1121
|.|...|.. :.:.:|..:.:|.:. ..||..|.|| :..:|.....:..|
Mouse 1767 HWLAQEEPVPVEELEGLEKQIWICRVAQHTCGGAEEEAKPSLSQHKLAAAELSFDSLASE----- 1826
Fly 1122 KSFSELKEL-----AGIDDLSIADKTV----LTSEMEDRLNTLLNTLLDKGDIVEALRLQELFEF 1177
.|||:|..| .|::|| ..||. |..:.::.||||:..|||.|.:.||.|:.:.|.|
Mouse 1827 LSFSKLAALNTSKYLGLNDL--PSKTTCENRLKHKEQESLNTLIGQLLDGGCVHEASRVCQYFRF 1889
Fly 1178 RPNDLRFIVFAMALAEGMTSISNLSSKERQLLG------EIEKSAFPKFNRITLNQNVITRWDSD 1236
...||..::...|||....::.:|.|:.|.||. ::|..:.| .|....
Mouse 1890 YSQDLVLVLHCRALASAEATMEDLHSEIRALLSSAAQPEDLESPSVP------------LRKAHS 1942
Fly 1237 LSDTCSDSVAMEFEEIPSKEKQQTLDTLLGIGSKLKYGVELGRRIVLAYRAAMYLDKEYLDVLRT 1301
.|...|.|..| ..|:.|..|.|.||: ||..:|....|:::..|..|..|...|.|| ..
Mouse 1943 SSSLDSQSFVM---VPPTDEVAQNLHTLI---SKCLHGKNYCRQVLCLYELAKDLGCSYGDV-AA 2000
Fly 1302 KDTGILLKSAAA----EDCLQRLLVVSDIQISTR-MTPKEIAECLALELTTCIVRPRFYIFHARE 1361
:|:..:|::..| :.|.| :.:.|:|: :....:||.:|.|:|..::.|.... ..:
Mouse 2001 RDSEAMLRAILASQRPDRCRQ-----AQVFINTQGLEADTVAELVAEEVTRELLTPSEGT--GEK 2058
Fly 1362 QPRNALRNADLWGHSIDRDFHLFLELAPNSTMLGNCLLEYCDALKTYRRYQEGKPFEETEAFENL 1426
||.| |.||::.|..|
Mouse 2059 QPFN--------------------------------------------------PAEESQTFLQL 2073
Fly 1427 SKII---TLYGL----PTPS-PTGTMSGIPQVLSHKKQNQIYVELLIKAHLCFVHECSMEGIVSV 1483
:.:. ||.|: ..|| |.|.:| ...||||.||.||...|.||||..|
Mouse 2074 TALCQDRTLVGMKLLDKIPSVPHGELS-------------CTTELLILAHHCFTFTCHMEGITRV 2125
Fly 1484 LQKAKAL-NTKLAQAKSWSLIVRLLIGIARYREMFYCFDSLIENEQFESLLGQFDEDQKGGLRQA 1547
||.|:.| :..||..:.:.|:||||.||.||.||.|.||.|.:...||.|:.: ..|..|.|:.|
Mouse 2126 LQAARMLTDNHLAPNEEYGLVVRLLTGIGRYNEMTYIFDLLHQKHYFEVLMRK-KLDPTGTLKTA 2189
Fly 1548 ILSYLREYQPKNGKELLRLAALHFLMYKELAEMWTTEAQEIVTKIQAFAAQS----NKLKCSVEV 1608
:|.|::..:| ...|...:.||.|.|.:|:. |..|....||....:| ..||...::
Mouse 2190 LLDYIKRCRP-GDSEKHNMIALCFSMCREIG-----ENHEAAACIQLKLIESQPWEESLKDGAQL 2248
Fly 1609 QTLLQQALENYTHATENYLLDNKLLLAQQSVSRAELMAMQLDLCNKALEKRHSNNANHLCVSVIG 1673
:.||.:||.....|.|:|..|:.:..|.......:|:.:|:...| :..|.:.:::
Mouse 2249 KQLLLKALTLMLDAAESYAKDSCVRQALHCNRLTKLITLQIHFLN--------SGQNTMLINL-- 2303
Fly 1674 VRSREQFRELVNVHLSVP---QALILSRAYGYDISWSEAILSQFVVLQG-VNYLQEYLCHQRIND 1734
..::|::..:::| ||.|::.||.:...|:| :|.|.|:|:| .:||:|:...:.:..
Mouse 2304 -----GHQKLMDCIMTLPRFYQASIVAEAYDFVPDWAE-VLYQQVILKGDFSYLEEFKQQKLLRP 2362
Fly 1735 DVIEQIVKGYLLHIQSNATNSKQEESMVQLVGLIKSVVLKYKLASILGFKSIVMSLIND 1793
::.|.|.|.|..| ....:..|::.:|:...:.:.|.||||....|..||..|:.|
Mouse 2363 NIFEDISKKYKQH----QPTDRVTENLKKLLSYCEDIYLYYKLAYEHKFFEIVNMLLKD 2417
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