Protein Alignment CG3649 and SLC17A6

DIOPT Version :9

• Sequence 1: NP_611725.2
• Gene: CG3649 / 37626
• FlyBaseID: FBgn0034785
• Length: 486
• Species: Drosophila melanogaster
• Sequence 2: NP_065079.1
• Gene: SLC17A6 / 57084
• HGNCID: 16703
• Length: 582
• Species: Homo sapiens
• Alignment Length: 446
• Identity: 135/446 - (30%)
• Similarity: 225/446 - (50%)
• Gaps: 39/446 - (8%)

  Fly    36 RFNMSVAIVAFTNANS-----------SNPNYPEYRLTEPQKSYTI-SSPFWGSCCTQMMSGYLS 88
            |.|:.||||...|.::           :..|:      :|:....| .|.|||...||:..||::
Human    88 RCNLGVAIVDMVNNSTIHRGGKVIKEKAKFNW------DPETVGMIHGSFFWGYIITQIPGGYIA 146

  Fly    89 SRFGAKVLLLTIMLLTALLSIATPFALAWGGWQLLFWVRFVQGLAMGGMWPCLYTHLAKWCPKKE 153
            ||..|..:....:|||:.|::..|.| |...:..:.:||.:|||..|..:|..:...:||.|..|
Human   147 SRLAANRVFGAAILLTSTLNMLIPSA-ARVHYGCVIFVRILQGLVEGVTYPACHGIWSKWAPPLE 210

  Fly   154 ANRMGGIMTTGLDCGTIMGFALSGVLSASPLGWPSTFYVPGYLGIVWCLTFLRYGANSPSESKFI 218
            .:|:......|...|.::...|:|:| ....||.|.|||.|..|:||.:.:|.....||::...|
Human   211 RSRLATTSFCGSYAGAVIAMPLAGIL-VQYTGWSSVFYVYGSFGMVWYMFWLLVSYESPAKHPTI 274

  Fly   219 SLAERKHIQFALEQNQVIRGATP--PVPWLQILTSRP---FIVLAFCKMSQACSFYTLMQQIPRY 278
            :..||::|:.::.::..:.||..  ..||.:..||.|   .||..||:   :.:||.|:...|.|
Human   275 TDEERRYIEESIGESANLLGAMEKFKTPWRKFFTSMPVYAIIVANFCR---SWTFYLLLISQPAY 336

  Fly   279 IHGIFHYSIAANALLSALPFVVM--LMSSYGFIFLAEYLTRRRDISLPILRKTINSFATWTPAVA 341
            ...:|.:.|:...:|||:|.:||  ::...|.|  |::|..::.:|...:||.:|.......|..
Human   337 FEEVFGFEISKVGMLSAVPHLVMTIIVPIGGQI--ADFLRSKQILSTTTVRKIMNCGGFGMEATL 399

  Fly   342 LVILSYVSDQNVVGSMFCLIAATAAISGQAI-GSSLNHVDLSPNFAGLLFGMSNTLMSAAGVISP 405
            |:::.|...:.|..|...|   ....||.|| |.::||:|::|.:|.:|.|:||.:.:.:|::.|
Human   400 LLVVGYSHTRGVAISFLVL---AVGFSGFAISGFNVNHLDIAPRYASILMGISNGVGTLSGMVCP 461

  Fly   406 IVIGLTVTKESDRSQWRTVFLGISVILFLGNLMYLIFGQMTVQSWNDSPSKETETE 461
            |::| .:||...|.:|:.|||..:::.:.|.:.|.||.....|.|.|  .:||..|
Human   462 IIVG-AMTKNKSREEWQYVFLIAALVHYGGVIFYAIFASGEKQPWAD--PEETSEE 514

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG3649	NP_611725.2	MFS	22..442	CDD:119392	127/425 (30%)
		2A0114euk	23..458	CDD:129972	132/441 (30%)
SLC17A6	NP_065079.1	MFS_SLC17A6_7_8_VGluT	74..498	CDD:340940	128/426 (30%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2532
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D497052at2759
OrthoFinder	1	1.000	-	-		FOG0000034
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	4	3.820