DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG3649 and slc17a8

DIOPT Version :9

Sequence 1:	NP_611725.2	Gene:	CG3649 / 37626	FlyBaseID:	FBgn0034785	Length:	486	Species:	Drosophila melanogaster
Sequence 2:	NP_001076304.1	Gene:	slc17a8 / 563467	ZFINID:	ZDB-GENE-060503-416	Length:	590	Species:	Danio rerio

Alignment Length:	436	Identity:	131/436 - (30%)
Similarity:	222/436 - (50%)	Gaps:	21/436 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly    36 RFNMSVAIVAFTNANSSNPN-----YPEYRLTEPQKSYTI-SSPFWGSCCTQMMSGYLSSRFGAK 94
            |.|:.||||...|.|:...|     .|.....:|:....| .|.|||...||:..|::|::..|.
Zfish    93 RCNLGVAIVEMVNNNTVYINGTAVMQPAQFNWDPETVGLIHGSFFWGYIVTQIPGGFISNKLAAN 157

  Fly    95 VLLLTIMLLTALLSIATPFALAWGGWQLLFWVRFVQGLAMGGMWPCLYTHLAKWCPKKEANRMGG 159
            .:....:.||::|::..|.| |...:..:.:||.:|||..|..:|..:...:||.|..|.:|:..
Zfish   158 RVFGAAIFLTSVLNMFIPSA-ARVHYGCVMFVRILQGLVEGVTYPACHGMWSKWAPPLERSRLAT 221

  Fly   160 IMTTGLDCGTIMGFALSGVLSASPLGWPSTFYVPGYLGIVWCLTFLRYGANSPSESKFISLAERK 224
            ....|...|.::...|:|:| ...:||||.||:.|..||:|.:.::....|||:....||..||.
Zfish   222 TSFCGSYAGAVIAMPLAGIL-VQYVGWPSVFYIYGVFGIIWYIFWILLAYNSPAVHPTISEEERN 285

  Fly   225 HIQFALEQNQVIRGATP--PVPWLQILTSRP---FIVLAFCKMSQACSFYTLMQQIPRYIHGIFH 284
            :|:.::.:...:..:|.  ..||.:..||.|   .||..||:   :.:||.|:...|.|...:|.
Zfish   286 YIETSIGEGANLMSSTEKFKTPWREFFTSMPVYAIIVANFCR---SWTFYLLLISQPAYFEEVFG 347

  Fly   285 YSIAANALLSALPFVVMLMSSYGFIFLAEYLTRRRDISLPILRKTINSFATWTPAVALVILSYVS 349
            :.|:...:|||:|.:||.:.......||::|..|:.:|...:||.:|.......|..|:::.: |
Zfish   348 FPISKVGILSAVPHMVMTIIVPIGGQLADFLRSRKILSTTTVRKIMNCGGFGMEATLLLVVGF-S 411

  Fly   350 DQNVVGSMFCLIAATAAISGQAI-GSSLNHVDLSPNFAGLLFGMSNTLMSAAGVISPIVIGLTVT 413
            ....|...|.::|  ...||.|| |.::||:|::|.:|.:|.|:||.:.:.:|::.|:::| .:|
Zfish   412 HTRAVAISFLILA--VGFSGFAISGFNVNHLDIAPRYASILMGISNGVGTLSGMVCPLIVG-ALT 473

  Fly   414 KESDRSQWRTVFLGISVILFLGNLMYLIFGQMTVQSWNDSPSKETE 459
            |...|.:|:.||:..|::.:.|.:.|.||.....|.|.|..:...|
Zfish   474 KHKTRLEWQHVFVIASMVHYTGVIFYAIFASGEKQDWADPENTSDE 519

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3649	NP_611725.2	MFS	22..442	CDD:119392	125/417 (30%)
CG3649	NP_611725.2	2A0114euk	23..458	CDD:129972	130/433 (30%)
slc17a8	NP_001076304.1	2A0114euk	75..514	CDD:129972	130/429 (30%)
		MFS	81..503	CDD:119392	126/418 (30%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	526..590
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170582531
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2532
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D497052at2759
OrthoFinder	1	1.000	-	-		FOG0000034
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	6	5.750