Protein Alignment CG3649 and SLC37A1

DIOPT Version :9

• Sequence 1: NP_611725.2
• Gene: CG3649 / 37626
• FlyBaseID: FBgn0034785
• Length: 486
• Species: Drosophila melanogaster
• Sequence 2: XP_011527916.1
• Gene: SLC37A1 / 54020
• HGNCID: 11024
• Length: 577
• Species: Homo sapiens
• Alignment Length: 553
• Identity: 116/553 - (20%)
• Similarity: 193/553 - (34%)
• Gaps: 170/553 - (30%)

  Fly    19 HLQVLFLFLCATLIVAQRFNMS-------------------VAIVAFTNANSSNPNYPEYRLTEP 64
            ||...|:|:...|:.|. |::|                   .|.|.|::.|..:.:...::|.:.
Human    49 HLYRAFIFILTFLLYAS-FHLSRKPISIVKGELHKYCTAWDEADVRFSSQNRKSGSAAPHQLPDN 112

  Fly    65 QKSYTISSPF-------------WGSCCTQMMSGYLSSRFGAKVLL---LTIMLL-----TALLS 108
            :.... .:||             :...|...:..|||...|.::.:   ||..:|     |||..
Human   113 ETDCG-WAPFDKNNYQQLLGALDYSFLCAYAVGMYLSGIIGERLPIRYYLTFGMLASGAFTALFG 176

  Fly   109 IATPFALAWGGWQLLFWVRFVQGLAMGGMWPCLYTHLAKWCPKKEANRMGGIMTTGLDCGTIMGF 173
            :...:.:...|:.::  .:.:.||.....||.:.|.|..|..|.....:.|:..:....|.|:|.
Human   177 LGYFYNIHSFGFYVV--TQVINGLVQTTGWPSVVTCLGNWFGKGRRGLIMGVWNSHTSVGNILGS 239

  Fly   174 ALSGVLSASPLGWPST-----FYVPG----YLGIVWCLTF------------------------- 204
            .::|.       |.||     |.|||    .:||| |..|
Human   240 LIAGY-------WVSTCWGLSFVVPGAIVAAMGIV-CFLFLIEHPNDVRCSSTLVTHSKGYENGT 296

  Fly   205 ---------LRYGANSP--SESKFISLAERKHIQFALEQNQVI------RGATPPVPWLQILTSR 252
                     |:...|.|  .|.:.:.|::.|.   ::..|.|:      ...|..:.:...|...
Human   297 NRLRLQKQILKSEKNKPLDPEMQCLLLSDGKG---SIHPNHVVILPGDGGSGTAAISFTGALKIP 358

  Fly   253 PFIVLAFCKMSQACSFYTLMQQIPRYIHGIFHYSIAANALLSALPFVVMLMSSYGFIF------- 310
            ..|..:.|.:......||.:..:|.||..:.|........||.| |.|      |.||
Human   359 GVIEFSLCLLFAKLVSYTFLFWLPLYITNVDHLDAKKAGELSTL-FDV------GGIFGGILAGV 416

  Fly   311 LAEYLTRRRD---ISLPILRKTINSFATWT-----PAVALVILS-------YV-----------S 349
            :::.|.:|..   :.|.:...|:..|:|.:     ..:|:::||       |.           :
Human   417 ISDRLEKRASTCGLMLLLAAPTLYIFSTVSKMGLEATIAMLLLSGALVSGPYTLITTAVSADLGT 481

  Fly   350 DQNVVGSMFCLIAATAAISGQ-AIGSSLNHVDLSPNFAGLL--FGMSNT---LMSAAGVISPIVI 408
            .:::.|:...|...||.|.|. ::|::     |.|..||||  .|.||.   ||.|.......::
Human   482 HKSLKGNAHALSTVTAIIDGTGSVGAA-----LGPLLAGLLSPSGWSNVFYMLMFADACALLEIL 541

  Fly   409 GLTV-----------TKESDRSQWRTVFLGISV 430
            .|..           |.|..|.:|  :|.|.||
Human   542 KLNFPTTYKIKYRLSTYELTRFKW--LFFGSSV 572

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG3649	NP_611725.2	MFS	22..442	CDD:119392	114/550 (21%)
		2A0114euk	23..458	CDD:129972	114/549 (21%)
SLC37A1	XP_011527916.1	UhpC	51..543	CDD:225180	105/518 (20%)
		MFS	129..489	CDD:119392	74/379 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165148674
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.840