DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG3649 and CG15096

DIOPT Version :9

Sequence 1:	NP_611725.2	Gene:	CG3649 / 37626	FlyBaseID:	FBgn0034785	Length:	486	Species:	Drosophila melanogaster
Sequence 2:	NP_611376.1	Gene:	CG15096 / 37170	FlyBaseID:	FBgn0034394	Length:	491	Species:	Drosophila melanogaster

Alignment Length:	468	Identity:	189/468 - (40%)
Similarity:	275/468 - (58%)	Gaps:	18/468 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly    16 GVRHLQVLFLFLCATLIVAQRFNMSVAIVAFTNANSSNPNYPEYRLTEPQKSYTISSPFWGSCCT 80
            ||||.|||.||...|:....|.|:|||:||.|:|.|.||::|||..:|..||..:||.|||...|
  Fly    34 GVRHFQVLLLFFALTVAYGCRVNLSVAVVAMTDAASVNPDFPEYNWSEKTKSLLLSSFFWGYVIT 98

  Fly    81 QMMSGYLSSRFGAKVLLLTIMLLTALLSIATPFALAWGGWQLLFWVRFVQGLAMGGMWPCLYTHL 145
            |:.:|.|:.::|.||::|:.:.:.::|:|.||.....|||||:..:|.|:||..|.::|..:|.|
  Fly    99 QVPAGQLARKYGGKVMILSGLAICSILNILTPICAKIGGWQLVCALRVVEGLCQGVVFPSTHTIL 163

  Fly   146 AKWCPKKEANRMGGIMTTGLDCGTIMGFALSGVLSASPLGWPSTFYVPGYLGIVWCLTFLRYGAN 210
            ::|.|.||...:|....:|...|||:..|.|||::|||:||||.||:.|.:|.||.:.:..:||.
  Fly   164 SQWAPPKERATLGTCAYSGNQFGTILMLATSGVIAASPIGWPSIFYISGGIGCVWSVVYFFFGAG 228

  Fly   211 SPSESKFISLAERKHIQFALEQNQVIRGATP-----PVPWLQILTSRPFIVLAFCKMSQACSFYT 270
            ||.|.|.||..|:|.|:.: :.::|..|...     |.|||...||..|:||..........|:|
  Fly   229 SPQECKSISAEEKKLIEMS-QADEVSGGQEQPKEQLPTPWLSFFTSPAFLVLIVSHSVHNWGFWT 292

  Fly   271 LMQQIPRYIHGIFHYSIAANALLSALPFVVMLMSSYGFIFLAEYLTRRRDISLPILRKTINSFAT 335
            |:.:||.|:..|....|.:|||||:||:|.|...|:.|..::..|..|..||....||..||...
  Fly   293 LLTEIPSYMKNILGKDIKSNALLSSLPYVCMFAMSFVFSSISAQLNNRNCISRSTSRKLFNSIGL 357

  Fly   336 WTPAVALVILSYVS-DQNVVGSMFCLIAATAAISGQA-IGSSLNHVDLSPNFAGLLFGMSNTLMS 398
            |.|.|.||.|.||: ||:.:..:  |:..|..::|.. :|.:.||:||||||||:|.|::|.:.:
  Fly   358 WIPMVTLVGLGYVNPDQSELAVV--LLCFTVGMNGATYLGFNTNHIDLSPNFAGILMGITNGVAN 420

  Fly   399 AAGVISPIVIGLTVTKESDRSQWRTVFLGISVILFLGNLMYLIFGQMTVQSWNDSPSKETETEAS 463
            ...:|:|:::|..||.|.|..|||.||...:....:||.:|:|||:..||.|||.|:|
  Fly   421 IMSIIAPLIVGFIVTNEHDPEQWRIVFFIAAGFYLVGNTLYVIFGKANVQPWNDPPAK------- 478

  Fly   464 PKPQASAPSVAEE 476
            |: :.|.|.|..:
  Fly   479 PR-RNSTPQVESQ 490

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3649	NP_611725.2	MFS	22..442	CDD:119392	170/426 (40%)
CG3649	NP_611725.2	2A0114euk	23..458	CDD:129972	179/441 (41%)
CG15096	NP_611376.1	2A0114euk	36..480	CDD:129972	183/453 (40%)
CG15096	NP_611376.1	MFS	40..464	CDD:119392	170/426 (40%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45442703
Domainoid	1	1.000	116	1.000	Domainoid score	I288
eggNOG	1	0.900	-	-		E1_KOG2532
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	134	1.000	Inparanoid score	I245
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D428976at33208
OrthoFinder	1	1.000	-	-		FOG0000034
OrthoInspector	1	1.000	-	-		mtm14983
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11662
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	9	8.900