DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG3649 and NaPi-T

DIOPT Version :9

Sequence 1:	NP_611725.2	Gene:	CG3649 / 37626	FlyBaseID:	FBgn0034785	Length:	486	Species:	Drosophila melanogaster
Sequence 2:	NP_001260981.1	Gene:	NaPi-T / 36651	FlyBaseID:	FBgn0016684	Length:	524	Species:	Drosophila melanogaster

Alignment Length:	495	Identity:	127/495 - (25%)
Similarity:	209/495 - (42%)	Gaps:	60/495 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    36 RFNMSVAIVAF-----------TNANSSN--------------------PNYP----EYRLTEPQ 65
            |.|:::.||..           |:.||::                    .|.|    .:...|.|
  Fly    25 RINLNITIVDMIAGKGAITSNETHENSTDLAALAEMNERFSLERWFLDWANIPYEKNGFHWNEKQ 89

  Fly    66 KSYTISSPFWGSCCTQMMSGYLSSRFGAKVLLLTIMLLTALLSIATPFALAWGGWQLLFWVRFVQ 130
            :...:.|.||.....|:..|.|::::|.|::......:........|....|....|:. :|..|
  Fly    90 QGALLGSFFWAHWTLQIPGGILATKYGTKLVFGWSNGIGVFCCFLIPIVSYWSYTGLII-LRVFQ 153

  Fly   131 GLAMGGMWPCLYTHLAKWCPKKEANRMGGIMTTGLDCGTIMGFALSGVLSASPLGWPSTFYVPGY 195
            |...|..||.::...|||.|..|.::..... .|...|..:.:.:.|.: .....|...:|:.|.
  Fly   154 GWITGLAWPSMHVLTAKWIPPNERSKFVSAY-LGSSVGVALFYPIFGYI-IDWTRWEWVYYICGI 216

  Fly   196 LGIVWCLTFLRYGANSPSESKFISLAERKHIQFALEQNQVIRGATPPVPWLQILTSRPFIVLAFC 260
            :|.:|.:.:.....:||:|...|:.:|||.|:.:|..:  |:|:..|.||..|.||||..:....
  Fly   217 VGTLWFIAWQFLVFDSPAEHPRIADSERKFIEKSLGAS--IQGSKGPTPWKAIATSRPVWLNVVA 279

  Fly   261 KMSQACSFYTLMQQIPRYIHGIFHYSIAANALLSALPFVVMLMSSYGFIFLAEYLTRRRDISLPI 325
            :.......:|||...|.|...|.|::|.|...||.||.::.::.:|.|...|:||.|...:|...
  Fly   280 QWGGIWGLFTLMTHAPTYFRLIHHWNIRATGFLSGLPHLMRMLFAYVFSIFADYLLRTDKMSRTN 344

  Fly   326 LRKTINSFATWTPAVALVILSYVSDQNVVGSMFCLIAATAAISGQAIGSSLNHVDLSPNFAGLLF 390
            :||........|..:.::.|:|.. .|...::..:..||......:.|...:.||||||:||::.
  Fly   345 VRKLATFICCGTKGLIVLALAYFG-YNATAAIVLVTVATMLHGAVSSGPLASMVDLSPNYAGIVL 408

  Fly   391 GMSNTLMSAAGVISPIVIGLTVTKESDRSQWRTVFLGISVILFLGNLMYLIFGQMTVQSWN---- 451
            |:|..:....|.|||.::|...........|:.|||..|::|....::|::|.:..:|.||
  Fly   409 GVSGMIGGMPGFISPFIVGQLTHNNQTIDAWKNVFLLTSLMLTGSGILYVLFSESKLQPWNSGCH 473

  Fly   452 ---DSPSKETET-------EASPKPQAS-----APSVAEE 476
               ||..||.:.       |...||..|     .|.|||:
  Fly   474 QLPDSGLKELQNLGRDQDDEEEKKPLKSDHDKETPIVAEQ 513

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3649	NP_611725.2	MFS	22..442	CDD:119392	111/440 (25%)
CG3649	NP_611725.2	2A0114euk	23..458	CDD:129972	118/463 (25%)
NaPi-T	NP_001260981.1	2A0114euk	1..474	CDD:129972	115/454 (25%)
NaPi-T	NP_001260981.1	MFS	76..460	CDD:119392	103/389 (26%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	116	1.000	Domainoid score	I288
eggNOG	1	0.900	-	-		E1_KOG2532
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	134	1.000	Inparanoid score	I245
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D497052at2759
OrthoFinder	1	1.000	-	-		FOG0000034
OrthoInspector	1	1.000	-	-		mtm14983
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11662
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	8	7.970